|
rs1555461176
|
|
AT |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs587776416
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs80358451
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs11655237
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<b>Background:</b> Two genome-wide association studies (GWASs) identified LINC00673 rs11655237 was associated with susceptibility to pancreatic cancer.
|
31118802 |
2019 |
|
rs1799939
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We suggest that molecular profiling of each patient's tumor for G691S RET SNP, potentially CXCR2 SNP, and also other yet-to-be identified SNP associated with pancreatic cancer will allow for both improved understanding of individual prognosis and allow for utilization of more personalized, targeted adjuvant therapies.
|
19057948 |
2009 |
|
rs4759313
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control study was conducted analysing rs1561927 and rs4759313 polymorphisms using DNA collected in a population-based case-control study of pancreatic cancer (111 pancreatic ductal adenocarcinoma cases (PDAC), 56 pancreatic neuroendocrine tumor (PNET), and 125 healthy controls).
|
30475759 |
2019 |
|
rs401681
|
|
T |
0.740 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
|
20101243 |
2010 |
|
rs3790844
|
|
T |
0.730 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
|
20101243 |
2010 |
|
rs9543325
|
|
C |
0.700 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
|
20101243 |
2010 |
|
rs1801282
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A haplotype including Pro12Ala was also significantly associated with pancreatic cancer risk in all subjects and in subjects randomized to vitamin A.
|
19436234 |
2009 |
|
rs1805192
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A haplotype including Pro12Ala was also significantly associated with pancreatic cancer risk in all subjects and in subjects randomized to vitamin A.
|
19436234 |
2009 |
|
rs199769221
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A relevant contribution of the Arg117His-mutation to pathogenesis of pancreatic cancer might be possible, since also asymptomatic individuals have been reported to carry this mutation and individuals with only mild symptoms may be undiagnosed as hp.
|
11062709 |
2000 |
|
rs401681
|
|
|
0.740 |
GeneticVariation |
BEFREE |
A small number of common susceptibility loci have been identified for pancreatic cancer, one of which is marked by rs401681 in the TERT-CLPTM1L gene region on chromosome 5p15.33.
|
25940397 |
2015 |
|
rs1801516
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A statistically significant interaction of ATM D1853N and LIG4 C54T genotype with diabetes on the risk of pancreatic cancer was also detected.
|
19147782 |
2009 |
|
rs786203926
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A statistically significant interaction of ATM D1853N and LIG4 C54T genotype with diabetes on the risk of pancreatic cancer was also detected.
|
19147782 |
2009 |
|
rs25489
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A tendency of association between Arg280His and PC was also detected in the dominant model (OR, 0.70; 95% CI, 0.48-1.00).
|
26418909 |
2016 |
|
rs3731055
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A total of 7 XPC tagging SNPs (tag-SNPs) were selected from the International HapMap Project Databases (rs2228001A/C, rs2470353G/C, rs2228000C/T, rs3731114C/G, rs3729587G/C, rs2607775C/G and rs3731055G/A) and were genotyped in 205 patients with PC and 230 non-cancer control subjects using a SNaPshot assay.
|
30344718 |
2018 |
|
rs4880
|
|
|
0.020 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |
|
rs747601652
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |
|
rs887303970
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |
|
rs1799895
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |
|
rs201753355
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |
|
rs1143684
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |
|
rs1143684
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |
|
rs1258159645
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, an association of functional polymorphisms in oxidative stress-modifying genes superoxide dismutase 2 (SOD2 [Ala16Val, rs4880]), SOD3 (Arg231Gly, rs1799895), nicotinamide adenine dinucleotide phosphate:quinone oxidoreductase (NQO1 [Pro187Ser, rs1800566], and NQO2 (Phe47Leu, rs1143684) with pancreatic cancer risk was studied.
|
20966810 |
2011 |