Gene: MTHFR ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE MTHFR gene C677T rather than A1298C polymorphism may be associated with PC. 31701291

2020
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE MTHFR gene C677T rather than A1298C polymorphism may be associated with PC. 31701291

2020
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE We performed a meta-analysis of all relevant case-control studies that examined the association between MTHFR C677T polymorphism and pancreatic cancer risk. 23098468

2012
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE This meta-analysis indicated that MTHFR polymorphisms (C667T and A1298C) are not associated with pancreatic cancer risk. 23167392

2012
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE This meta-analysis indicated that MTHFR polymorphisms (C667T and A1298C) were not associated with pancreatic cancer risk. 22901202

2012
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE The risk for PC was higher in individuals with MTHFR C677T or TT polymorphisms and a smoking habit (OR = 2.52, 95% CI = 1.05-6.09, P = 0.04). 21441790

2011
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE We conducted a case-control study to assess the effect of alcohol on pancreatic cancer in conjunction with polymorphisms in one-carbon metabolism enzymes, methylenetetrahydrofolate reductase (MTHFR C677T), methionine synthase (MTR A2756G), methionine synthase reductase (MTRR A66G), and thymidylate synthase (TS) variable number of tandem repeat. 18843018

2008
dbSNP: rs1217691063
rs1217691063
MTHFR
0.050 GeneticVariation BEFREE Joint effect between MTHFR C677T polymorphism and smoking or drinking increased risk of pancreatic cancer in a super-multiplicative manner. 16234002

2005
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE First, we performed a case-control study of germline MTHFR polymorphisms (C677T, A1298C) in 303 patients with pancreatic cancer and 305 matched control subjects. 16234003

2005
dbSNP: rs397507444
rs397507444
MTHFR
0.050 GeneticVariation BEFREE We found that the C667T (but not the A1298C) polymorphism had a significant main effect on the risk of pancreatic cancer. 15941958

2005