The expression level of STAT3 protein in tumor tissues of patients with <i>STAT3</i> rs1053004 locus GG genotype was significantly higher than in patients with type GA, and it was the lowest in patients with type AA.<b>Conclusion:</b> Polymorphisms in the <i>SP1</i> rs1353058818 and <i>STAT3</i> rs1053004 loci are associated with the risk of human TSCC.
The expression level of STAT3 protein in tumor tissues of patients with <i>STAT3</i> rs1053004 locus GG genotype was significantly higher than in patients with type GA, and it was the lowest in patients with type AA.<b>Conclusion:</b> Polymorphisms in the <i>SP1</i> rs1353058818 and <i>STAT3</i> rs1053004 loci are associated with the risk of human TSCC.