Gene: NRAS ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121434596
rs121434596
NRAS
0.810 GeneticVariation UNIPROT American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. 24493721

2014
dbSNP: rs121913237
rs121913237
NRAS
0.810 GeneticVariation UNIPROT American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers. 24493721

2014
dbSNP: rs121434596
rs121434596
NRAS
0.810 GeneticVariation BEFREE We report the case of a child with a diagnosis of JMML carrying two mutations of NRAS gene (c.37G>C and c.38G>A) independently occurring in long-term culture initiating cells. 22183880

2012
dbSNP: rs121913237
rs121913237
NRAS
0.810 GeneticVariation BEFREE In the present study, we report 2 patients with somatic mosaicism for oncogenic NRAS mutations (G12D and G12S) associated with the development of JMML. 22753870

2012
dbSNP: rs121434596
rs121434596
NRAS
0.810 GeneticVariation UNIPROT Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. 17332249

2007
dbSNP: rs121913237
rs121913237
NRAS
0.810 GeneticVariation UNIPROT Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. 17332249

2007
dbSNP: rs121434596
rs121434596
NRAS
T 0.810 CausalMutation CLINVAR

dbSNP: rs121913237
rs121913237
NRAS
T 0.810 CausalMutation CLINVAR

dbSNP: rs121913250
rs121913250
NRAS
0.710 GeneticVariation BEFREE In the present study, we report 2 patients with somatic mosaicism for oncogenic NRAS mutations (G12D and G12S) associated with the development of JMML. 22753870

2012
dbSNP: rs121913250
rs121913250
NRAS
T 0.710 CausalMutation CLINVAR A restricted spectrum of NRAS mutations causes Noonan syndrome. 19966803

2010
dbSNP: rs121913250
rs121913250
NRAS
T 0.710 CausalMutation CLINVAR Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia. 19047918

2009
dbSNP: rs121913250
rs121913250
NRAS
T 0.710 CausalMutation CLINVAR Hyperactive Ras in developmental disorders and cancer. 17384584

2007
dbSNP: rs121913250
rs121913250
NRAS
T 0.710 CausalMutation CLINVAR Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies. 16518851

2006
dbSNP: rs121913250
rs121913250
NRAS
T 0.710 CausalMutation CLINVAR Juvenile myelomonocytic leukemia and Noonan syndrome. 10598665

2000
dbSNP: rs1057519695
rs1057519695
NRAS
0.010 GeneticVariation BEFREE Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia. 27145535

2016
dbSNP: rs1057519834
rs1057519834
NRAS
0.010 GeneticVariation BEFREE Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia. 27145535

2016
dbSNP: rs11554290
rs11554290
NRAS
0.010 GeneticVariation BEFREE Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia. 27145535

2016
dbSNP: rs121434595
rs121434595
NRAS
0.010 GeneticVariation BEFREE We report the case of a child with a diagnosis of JMML carrying two mutations of NRAS gene (c.37G>C and c.38G>A) independently occurring in long-term culture initiating cells. 22183880

2012