|
rs4986790
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Altered Th17 Cytokine Expression in Helicobacter pylori Patients with TLR4 (D299G) Polymorphism.
|
26853914 |
2016 |
|
rs4986790
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the pathogenesis of Helicobacter pylori related gastroduodenal diseases in relation to gastric secretion and inflammation.
|
26161647 |
2015 |
|
rs4986790
|
|
|
0.060 |
GeneticVariation |
BEFREE |
However, we detected that A allele carriers of the TLR4 Asp299Gly polymorphism might have an increase risk of gastric cancer in the Helicobacter pylori-positive population (G allele vs. A allele: OR=2.01, 95%CI: 1.22, 3.31).
|
24007538 |
2013 |
|
rs4986790
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was no association between TLR4 Asp299Gly polymorphism and any type of lesions, except for a slight nonsignificant increase in risk of IM associated with the AA genotype among subjects with a higher histological HP score.
|
17171451 |
2007 |
|
rs4986790
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A Toll-like receptor-4 (TLR-4) Asp299Gly and Thr399Ileu substitution reduces responsiveness to Helicobacter pylori (H. pylori) lipopolysaccharide.
|
18082569 |
2007 |
|
rs4986790
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We genotyped 87 patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma, 594 Helicobacter pylori positive controls and 358 healthy blood donors to investigate an association of TLR4 Asp299Gly in the development of gastric MALT lymphoma.
|
16019531 |
2005 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Several studies have reported that multidrug resistance gene 1 (MDR1) C3435T polymorphism was associated with the rate of Helicobacter pylori (H. pylori) eradication in proton pump inhibitor (PPI)-based triple therapy.
|
28353592 |
2017 |
|
rs1045642
|
|
|
0.020 |
GeneticVariation |
BEFREE |
P-glycoprotein expression in Helicobacter pylori-positive patients: the influence of MDR1 C3435T polymorphism.
|
22788927 |
2012 |
|
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This study aimed to examine the associations of the miR-146a G/C (rs2910164) and TLR4 +3725 G/C (rs11536889) polymorphisms with the risk of Helicobacter pylori (H. pylori) infection, gastric atrophy, and gastric cancer in a Japanese population.
|
20721625 |
2011 |
|
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We evaluated the associations of three SNPs (rs11614913, rs2910164, and rs3746444) in pre-miRNAs (miR-196a2, miR-146a, and miR-499) with the risk of gastric cancer (GC) and peptic ulcer diseases, and with the severity of Helicobacter pylori-induced gastritis in Japanese population.
|
21073609 |
2010 |
|
rs20417
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Helicobacter pylori positive patients and those with the COX-2 rs20417 polymorphism had a higher risk of developing GC.
|
31045826 |
2019 |
|
rs1057317
|
|
|
0.010 |
GeneticVariation |
BEFREE |
It was found that, in HP-positive patient, the AA genotype of the rs1057317 polymorphism was closely associated with the risk of GC (95% confidence interval, 1.12 to 2.70; odds ratio, 1.74; P = 0.0129).
|
30242897 |
2018 |
|
rs3761548
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we investigated IL-35 levels and a single nucleotide polymorphism, rs3761548, in FOXP3 gene in Helicobacter pylori-infected patients with peptic ulcer (PU), to clarify possible associations.
|
29938865 |
2018 |
|
rs1250915035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of our study was to investigate the impact of interleukin (IL)-6 190C/T, IL-6 174G/C, IL-6 572G/C, tumor necrosis factor-alpha (TNF-α) 308G/A, and angiotensin-converting enzyme (ACE) I/D gene polymorphisms on Helicobacter pylori (H. pylori) infection in children.A cross-sectional study was performed on 126 children (57 children with H. pylori infection and 69 children without H. pylori infection) aged between 3 and 18 years presenting to a Pediatrics Tertiary Hospital from Romania.
|
28746216 |
2017 |
|
rs747126003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of our study was to investigate the impact of interleukin (IL)-6 190C/T, IL-6 174G/C, IL-6 572G/C, tumor necrosis factor-alpha (TNF-α) 308G/A, and angiotensin-converting enzyme (ACE) I/D gene polymorphisms on Helicobacter pylori (H. pylori) infection in children.A cross-sectional study was performed on 126 children (57 children with H. pylori infection and 69 children without H. pylori infection) aged between 3 and 18 years presenting to a Pediatrics Tertiary Hospital from Romania.
|
28746216 |
2017 |
|
rs895819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MiR-27a rs895819 is involved in increased atrophic gastritis risk, improved gastric cancer prognosis and negative interaction with Helicobacter pylori.
|
28150722 |
2017 |
|
rs1002765
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to explore the interaction of the let-7e rs8111742, miR-365b rs121224, and miR-4795 rs1002765 single nucleotide polymorphisms (SNPs) with SNPs of the predicted target gene PGC and Helicobacter pylori status in GC and atrophic gastritis (AG) risk.
|
26988755 |
2016 |
|
rs121224
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to explore the interaction of the let-7e rs8111742, miR-365b rs121224, and miR-4795 rs1002765 single nucleotide polymorphisms (SNPs) with SNPs of the predicted target gene PGC and Helicobacter pylori status in GC and atrophic gastritis (AG) risk.
|
26988755 |
2016 |
|
rs4986791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the pathogenesis of Helicobacter pylori related gastroduodenal diseases in relation to gastric secretion and inflammation.
|
26161647 |
2015 |
|
rs1800896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Eight single nucleotide polymorphisms were associated with spontaneous production of IL-10 in culture, of which three (rs1800896 and rs1878672, p = .04; rs3024491, p = .01) were strongly associated with infection by Helicobacter pylori.
|
24628819 |
2014 |
|
rs1878672
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Eight single nucleotide polymorphisms were associated with spontaneous production of IL-10 in culture, of which three (rs1800896 and rs1878672, p = .04; rs3024491, p = .01) were strongly associated with infection by Helicobacter pylori.
|
24628819 |
2014 |
|
rs3024491
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Eight single nucleotide polymorphisms were associated with spontaneous production of IL-10 in culture, of which three (rs1800896 and rs1878672, p = .04; rs3024491, p = .01) were strongly associated with infection by Helicobacter pylori.
|
24628819 |
2014 |
|
rs5743618
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TLR1 1805T/G showed statistical differences when the control (Hp-) and infected (Hp+) groups (P = 0.041*) were compared; the TLR1 1805G allele had a protective effect towards infection (OR = 0.1; 95% CI = 0.01-0.88, P = 0.033*).
|
24754375 |
2014 |
|
rs601338
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Helicobacter pylori serologic status has no influence on the association between fucosyltransferase 2 polymorphism (FUT2 461 G->A) and vitamin B-12 in Europe and West Africa.
|
22237057 |
2012 |
|
rs11536889
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study aimed to examine the associations of the miR-146a G/C (rs2910164) and TLR4 +3725 G/C (rs11536889) polymorphisms with the risk of Helicobacter pylori (H. pylori) infection, gastric atrophy, and gastric cancer in a Japanese population.
|
20721625 |
2011 |