Gene: MTR ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1805087
rs1805087
MTR
0.050 GeneticVariation BEFREE Human methionine synthase A2756G polymorphism increases susceptibility to prostate cancer. 30064122

2018
dbSNP: rs1805087
rs1805087
MTR
0.050 GeneticVariation BEFREE Thus, the common polymorphism (rs1805087) of <i>METH</i> may be associated with increased prostate cancer risk. 30337500

2018
dbSNP: rs1805087
rs1805087
MTR
0.050 GeneticVariation BEFREE Genetic polymorphisms in MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) genes associated with pathological characteristics of prostate cancer in the Ecuadorian population. 23459165

2013
dbSNP: rs1805087
rs1805087
MTR
0.050 GeneticVariation BEFREE In a meta-analysis of folate-pathway polymorphisms, MTR 2756A > G (eight studies, OR = 1.06; 95% CI 1.00, 1.12; P = 0.06) and SHMT1 1420C > T (two studies, OR = 1.11; 95% CI 1.00, 1.22; P = 0.05) were positively associated with prostate cancer risk. 23724740

2013
dbSNP: rs1805087
rs1805087
MTR
0.050 GeneticVariation BEFREE Vitamin B(12), holo-haptocorrin, and the folate-pathway single-nucleotide polymorphisms MTR 2756A>G and SHMT1 1420C>T have been associated with an increased risk of prostate cancer. 20852008

2010
dbSNP: rs201765376
rs201765376
MTR
0.020 GeneticVariation BEFREE In a meta-analysis of folate-pathway polymorphisms, MTR 2756A > G (eight studies, OR = 1.06; 95% CI 1.00, 1.12; P = 0.06) and SHMT1 1420C > T (two studies, OR = 1.11; 95% CI 1.00, 1.22; P = 0.05) were positively associated with prostate cancer risk. 23724740

2013
dbSNP: rs201765376
rs201765376
MTR
0.020 GeneticVariation BEFREE Vitamin B(12), holo-haptocorrin, and the folate-pathway single-nucleotide polymorphisms MTR 2756A>G and SHMT1 1420C>T have been associated with an increased risk of prostate cancer. 20852008

2010
dbSNP: rs1131450
rs1131450
MTR
0.010 GeneticVariation BEFREE The rs28372871 GG genotype (adjusted OR = 1.40, P = 0.004) and rs11</span>31450 AA genotype (adjusted OR = 1.64, P = 0.007) exhibited 1.40-fold and 1.64-fold higher risk of PCa, respectively, compared with their respective homozygous wild-type genotypes. 27808252

2016
dbSNP: rs28372871
rs28372871
MTR
0.010 GeneticVariation BEFREE The rs28372871 GG genotype (adjusted OR = 1.40, P = 0.004) and rs1131450 AA genotype (adjusted OR = 1.64, P = 0.007) exhibited 1.40-fold and 1.64-fold higher risk of PCa, respectively, compared with their respective homozygous wild-type genotypes. 27808252

2016