Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs738409
rs738409
PNPLA3
0.900 GeneticVariation BEFREE The rs738409 G allele was significantly associated with NAFLD (P < 0.001; OR 2.8 95%, CI 1.5-5.2), independent of age, sex, body mass index (BMI), and Homeostasis Model Assessment (HOMA) index. 19738004

2009
dbSNP: rs1799883
rs1799883
FABP2
0.010 GeneticVariation BEFREE In conclusion, the present study demonstrates that the polymorphism Ala54Thr of FABP in patients with NAFLD doesn't predict liver histological changes, nor both insulin resistance and serum adipokines variations. 19961041

2010
dbSNP: rs773641005
rs773641005
GOT2
0.010 GeneticVariation BEFREE In conclusion, the present study demonstrates that the polymorphism Ala54Thr of FABP in patients with NAFLD doesn't predict liver histological changes, nor both insulin resistance and serum adipokines variations. 19961041

2010
dbSNP: rs738409
rs738409
PNPLA3
0.900 GeneticVariation BEFREE A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. 20034933

2010
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.050 GeneticVariation BEFREE Therefore, the H63D</span> mutation may increase susceptibility to NAFLD probably associated with peripheral iron overload, especially in males. 20216079

2010
dbSNP: rs1800730
rs1800730
HFE ; LOC108783645
0.010 GeneticVariation BEFREE The incidence and significance of HFE mutations (C282Y, H63D, and S65C) in nonalcoholic fatty liver disease (NAFLD) has not been investigated in Korea. 20216079

2010
dbSNP: rs2854116
rs2854116
APOC3
0.060 GeneticVariation BEFREE In 95 healthy Asian Indian men, a group known to have a high prevalence of nonalcoholic fatty liver disease, we genotyped two single-nucleotide polymorphisms (SNPs) in the gene encoding apolipoprotein C3 (APOC3) that are known to be associated with hypertriglyceridemia (rs2854116 [T-455C] and rs2854117 [C-482T]). 20335584

2010
dbSNP: rs2854117
rs2854117
APOC3
0.060 GeneticVariation BEFREE In 95 healthy Asian Indian men, a group known to have a high prevalence of nonalcoholic fatty liver disease, we genotyped two single-nucleotide polymorphisms (SNPs) in the gene encoding apolipoprotein C3 (APOC3) that are known to be associated with hypertriglyceridemia (rs2854116 [T-455C] and rs2854117 [C-482T]). 20335584

2010
dbSNP: rs738409
rs738409
PNPLA3
0.900 GeneticVariation BEFREE Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. 20373368

2010
dbSNP: rs780094
rs780094
GCKR
0.790 GeneticVariation BEFREE Genetic variation in GCKR gene rs780094 polymorphism contributes to the risk of NAFLD in Chinese people. 20625834

2011
dbSNP: rs738409
rs738409
PNPLA3
0.900 GeneticVariation BEFREE The G allele of rs738409 in PNPLA3 was associated with increased odds of histologic NAFLD (odds ratio [OR] = 3.26, 95% confidence intervals [CI] = 2.11-7.21; P = 3.6 x 10(-43)). 20648472

2010
dbSNP: rs738409
rs738409
PNPLA3
0.900 GeneticVariation BEFREE The PNPLA3 rs738409 polymorphism is associated with steatosis severity, hepatocellular ballooning, lobular inflammation, and perivenular fibrosis in pediatric NAFLD. 20648474

2010
dbSNP: rs738409
rs738409
PNPLA3
0.900 GeneticVariation BEFREE After adjustment for age, sex, diabetes, and alcohol consumption, the minor allele of rs738409 C/G, a nonsynonymous coding SNP in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) (adiponutrin) gene encoding an Ile148Met change, was associated with steatosis (P = 0.03), portal inflammation (P = 2.5 x 10(-4)), lobular inflammation (P = 0.005), Mallory-Denk bodies (P = 0.015), NAFLD activity score (NAS, P = 0.004), and fibrosis (P = 7.7 x 10(-6)). 20684021

2010
dbSNP: rs2645424
rs2645424
FDFT1
A 0.820 GeneticVariation GWASCAT In multivariate models adjusted for age, body mass index, diabetes, waist/hip ratios, and levels of glycated hemoglobin, the NAFLD activity score was associated with the SNP rs2645424 on chromosome 8 in farnesyl diphosphate farnesyl transferase 1 (FDFT1) (P = 6.8 × 10(-7)). 20708005

2010
dbSNP: rs2645424
rs2645424
FDFT1
A 0.820 GeneticVariation GWASDB In multivariate models adjusted for age, body mass index, diabetes, waist/hip ratios, and levels of glycated hemoglobin, the NAFLD activity score was associated with the SNP rs2645424 on chromosome 8 in farnesyl diphosphate farnesyl transferase 1 (FDFT1) (P = 6.8 × 10(-7)). 20708005

2010
dbSNP: rs2645424
rs2645424
FDFT1
0.820 GeneticVariation BEFREE In multivariate models adjusted for age, body mass index, diabetes, waist/hip ratios, and levels of glycated hemoglobin, the NAFLD activity score was associated with the SNP rs2645424 on chromosome 8 in farnesyl diphosphate farnesyl transferase 1 (FDFT1) (P = 6.8 × 10(-7)). 20708005

2010
dbSNP: rs343064
rs343064 		A 0.810 GeneticVariation GWASDB Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs343064
rs343064 		A 0.810 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs643608
rs643608 		G 0.800 GeneticVariation GWASDB Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs643608
rs643608 		G 0.800 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs1227756
rs1227756
COL13A1
G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs2710833
rs2710833
DDX60L ; LOC107986198
A 0.700 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs6487679
rs6487679 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs6591182
rs6591182
EHBP1L1
A 0.700 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010
dbSNP: rs887304
rs887304
CRACR2A
A 0.700 GeneticVariation GWASCAT Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. 20708005

2010