Gene: CDC42 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Macrothrombocytopenia and developmental delay with a de novo CDC42 mutation: Yet another locus for thrombocytopenia and developmental delay. 26386261

2015
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Macrothrombocytopenia and developmental delay with a de novo CDC42 mutation: Yet another locus for thrombocytopenia and developmental delay. 26386261

2015
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. 23382385

2013
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties. 24059268

2013
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Characterization of a Cdc42 protein inhibitor and its use as a molecular probe. 23382385

2013
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Dual lipidation of the brain-specific Cdc42 isoform regulates its functional properties. 24059268

2013
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines. 22266952

2012
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Expression analysis of Cdc42 in lung cancer and modulation of its expression by curcumin in lung cancer cell lines. 22266952

2012
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Local, persistent activation of Rho GTPases during plasticity of single dendritic spines. 21423166

2011
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Cdc42 in oncogenic transformation, invasion, and tumorigenesis. 21515363

2011
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Cdc42 in oncogenic transformation, invasion, and tumorigenesis. 21515363

2011
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Local, persistent activation of Rho GTPases during plasticity of single dendritic spines. 21423166

2011
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR RHO GTPase signaling for axon extension: is prenylation important? 20878268

2010
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Cdc42 and vesicle trafficking in polarized cells. 20633244

2010
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Cdc42 and vesicle trafficking in polarized cells. 20633244

2010
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR RHO GTPase signaling for axon extension: is prenylation important? 20878268

2010
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Kainic acid-induced F-344 rat model of mesial temporal lobe epilepsy: gene expression and canonical pathways. 19700661

2009
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Kainic acid-induced F-344 rat model of mesial temporal lobe epilepsy: gene expression and canonical pathways. 19700661

2009
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Further delineation of deletion 1p36 syndrome in 60 patients: a recognizable phenotype and common cause of developmental delay and mental retardation. 18245432

2008
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. 19092927

2008
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR Molecular basis of dendritic arborization. 18511961

2008
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation. 19092927

2008
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Molecular basis of dendritic arborization. 18511961

2008
dbSNP: rs797044916
rs797044916
CDC42
G 0.700 CausalMutation CLINVAR Further delineation of deletion 1p36 syndrome in 60 patients: a recognizable phenotype and common cause of developmental delay and mental retardation. 18245432

2008
dbSNP: rs797044870
rs797044870
CDC42
G 0.700 CausalMutation CLINVAR GEFs and GAPs: critical elements in the control of small G proteins. 17540168

2007