rs1259867035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS.
|
30381540 |
2018 |
rs746639990
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS.
|
30381540 |
2018 |
rs822396
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study has confirmed that ADIPOQ -3971A>G (rs822396) and +276G>T (rs1501299) polymorphism may be clinically helpful to estimate obesity and MetS risk in North Indian Punjabi population.
|
30265726 |
2018 |
rs1391272583
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome.
|
24432991 |
2014 |
rs17300539
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In contrast, both measured genotype and cross-sectional analysis failed to detect an association between the SNP rs17300539 with traits and clusters of metabolic syndrome.
|
23845780 |
2013 |
rs17300539
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The present study investigated whether the adiponectin gene promoter variant -11391 G/A (rs17300539) could predict the risk of developing traits characterizing the metabolic syndrome (MetS) and the impact of weight management.
|
18949681 |
2009 |
rs185847354
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The I164T mutation in the adiponectin gene was a common genetic background associated with the metabolic syndrome and CAD in the Japanese population.
|
15063429 |
2004 |
rs185847354
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results suggest that I164T mutation is associated with hypoadiponectinemia through disturbed secretion into plasma, which may contribute to the development of the metabolic syndrome.
|
12788102 |
2003 |
rs185847354
|
|
|
0.030 |
GeneticVariation |
BEFREE |
All the subjects carrying I164T mutation showed some feature of metabolic syndrome, including hypertension, hyperlipidemia, diabetes, and atherosclerosis.
|
12086969 |
2002 |
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The present study has confirmed that ADIPOQ -3971A>G (rs822396) and +276G>T (rs1501299) polymorphism may be clinically helpful to estimate obesity and MetS risk in North Indian Punjabi population.
|
30265726 |
2018 |
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
rs1501299 Polymorphism in the Adiponectin Gene and Their Association with Total Adiponectin Levels, Insulin Resistance and Metabolic Syndrome in Obese Subjects.
|
27915341 |
2016 |
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Then we comprehensively reviewed the association between ADIPOQ rs2241766/rs266729/rs1501299 and metabolic syndrome in the Chinese populations via a meta-analysis.
|
23593121 |
2013 |
rs1501299
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The SNP rs1501299 (G276T) in ADIPOQ gene was found associated with the presence of HTN in MetS (odds ratio for GG+GT vs. TT = 2.46; 95% CI: 1.14-5.3, p = 0.02), but not rs2241766 (T45G).
|
21637762 |
2011 |
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
<i>Results</i>: We found that CRC patients (N=75) with genotype rs266729G/C or carriers of G allele were associated with a significantly increased risk of MetS development (OR =2.9) compared to those with CC genotype (N=30).
|
28529612 |
2017 |
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
<i>Conclusions</i>: Our findings show that APN rs266729 G/C polymorphism is associated with lower APN levels in CRC patients, indicating that decreased circulating levels of APN may be a determinant risk factor for CRC in MetS patients.
|
28529612 |
2017 |
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Better designed studies with different ethnic populations and larger sample sizes are needed for assessing the relationship between ADIPOQ rs2241766 and rs266729 polymorphisms and MS in the future.
|
27554120 |
2016 |
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The study also sought to identify links between two polymorphisms, -11377C>G (rs266729) and +45T>G (rs2241766) of the adiponectin gene, in relation to adiponectin levels and the metabolic syndrome.
|
24561985 |
2014 |
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
No association was detected between SNP rs266729 and other clusters of metabolic syndrome or their traits except for HOMA-IR and fasting plasma insulin levels, p-values 0.035 and 0.004, respectively.
|
23845780 |
2013 |
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Then we comprehensively reviewed the association between ADIPOQ rs2241766/rs266729</span>/rs1501299 and metabolic syndrome in the Chinese populations via a meta-analysis.
|
23593121 |
2013 |
rs266729
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A reduction in plasma SFAs could be expected to lower insulin resistance in MetS subjects who are minor allele carriers of rs266729 in ADIPOQ and rs10920533 in ADIPOR1.
|
20032495 |
2010 |
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We conclude that the relationship between the habitual consumption of certain food groups and ADIPOQ indicates the need for further studies to develop a better understanding of this relationship; however, there was no association between the ADIPOQ + 45T> G gene polymorphism and metabolic syndrome in the group of elderly studied.
|
29313754 |
2019 |
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS.
|
30381540 |
2018 |
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
G allele of ADIPOQ rs2241766 increases the risk of MS.
|
27554120 |
2016 |
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Many previous studies have provided evidence that the ADIPOQ +45T>G polymorphism (rs2241766) might cause metabolic syndrome (MS).
|
27578536 |
2016 |
rs2241766
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The study also sought to identify links between two polymorphisms, -11377C>G (rs266729) and +45T>G (rs2241766) of the adiponectin gene, in relation to adiponectin levels and the metabolic syndrome.
|
24561985 |
2014 |