|
rs1012068
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
|
21725309 |
2011 |
|
rs1012068
|
|
G |
0.800 |
GeneticVariation |
GWASDB |
Variation in the DEPDC5 locus is associated with progression to hepatocellular carcinoma in chronic hepatitis C virus carriers.
|
21725309 |
2011 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MDR1 gene C3435T polymorphism in chronic hepatitis C patients.
|
29155127 |
2018 |
|
rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Urinary 8-hydroxydeoxyguanosine in relation to XRCC1 rs25487 G/A (Arg399Gln) and OGG1 rs1052133 C/G (Ser326Cys) DNA repair genes polymorphisms in patients with chronic hepatitis C and related hepatocellular carcinoma.
|
31354343 |
2019 |
|
rs10741657
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The well-known associations between CYP2R1 (rs1993116, rs10741657), GC (rs2282679), and DHCR7 (rs7944926, rs12785878) genotypes and 25(OH)D3 serum levels were also apparent in patients with chronic hepatitis C. The same genotypes of these single nucleotide polymorphisms (SNPs) that are associated with reduced 25(OH)D3 serum levels were found to be associated with HCV-related HCC (P = 0.07 [OR = 1.13, 95% CI = 0.99-1.28] for CYP2R1, P = 0.007 [OR = 1.56, 95% CI = 1.12-2.15] for GC, P = 0.003 [OR = 1.42, 95% CI = 1.13-1.78] for DHCR7; ORs for risk genotypes).
|
23734184 |
2013 |
|
rs10776934
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.
|
22095909 |
2012 |
|
rs10776934
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.
|
22095909 |
2012 |
|
rs10789491
|
|
G |
0.800 |
GeneticVariation |
GWASDB |
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.
|
22095909 |
2012 |
|
rs10789491
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.
|
22095909 |
2012 |
|
rs10814325
|
|
|
0.010 |
GeneticVariation |
BEFREE |
RECK Gene Promoter rs10814325 Polymorphism in Egyptian Patients with Hepatocellular Carcinoma on Top of Chronic Hepatitis C Viral Infection.
|
27268601 |
2016 |
|
rs10877012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Associations between a functionally relevant polymorphism in the gene encoding the vitamin D 1α-hydroxylase (CYP27B1-1260 rs10877012) and the response to treatment with pegylated interferon-α (PEG-IFN-α) and ribavirin were determined in 701 patients with chronic hepatitis C. In addition, associations between serum concentrations of 25-hydroxyvitamin D(3) (25[OH]D(3)) and treatment outcome were analysed.
|
22808108 |
2012 |
|
rs1126579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay.
|
29948377 |
2018 |
|
rs1127354
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the current study, 100 Iranian patients with chronic hepatitis C were examined and genotyped for ITPA rs1127354 and rs7270101 gene polymorphisms.
|
29660762 |
2018 |
|
rs1127354
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Patients with genotype 1b chronic hepatitis C (n = 446) treated with peg-interferon alpha and ribavirin (RBV) for 48 weeks were genotyped for the ITPA (rs1127354) and IL28B (rs8099917) genes.
|
23297176 |
2013 |
|
rs1127354
|
|
A |
0.850 |
GeneticVariation |
GWASCAT |
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.
|
20173735 |
2010 |
|
rs1127354
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Association of ITPA polymorphisms rs6051702/rs1127354 instead of rs7270101/rs1127354 as predictor of ribavirin-associated anemia in chronic hepatitis C treated patients.
|
23933495 |
2013 |
|
rs1127354
|
|
|
0.850 |
GeneticVariation |
BEFREE |
ITPA gene polymorphism (94C>A) effects on ribavirin-induced anemia during therapy in Egyptian patients with chronic hepatitis C.
|
28480960 |
2017 |
|
rs1127354
|
|
|
0.850 |
GeneticVariation |
BEFREE |
rs1127354 polymorphisms are associated with hemoglobin levels in Chinese patients with chronic hepatitis C treated with ribavirin/interferon.
|
31359493 |
2020 |
|
rs1127354
|
|
A |
0.850 |
GeneticVariation |
GWASDB |
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C.
|
20173735 |
2010 |
|
rs11506105
|
|
|
0.010 |
GeneticVariation |
BEFREE |
EGFR rs11506105 and IFNL3 SNPs but not rs8099917 are strongly associated with treatment responses in Iranian patients with chronic hepatitis C.
|
28703131 |
2017 |
|
rs11697186
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.
|
21659334 |
2011 |
|
rs11697186
|
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.
|
21659334 |
2011 |
|
rs11697186
|
|
T |
0.800 |
GeneticVariation |
GWASDB |
Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.
|
21659334 |
2011 |
|
rs11697186
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.
|
21659334 |
2011 |
|
rs11854484
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The newly identified association between RBV serum levels and SLC28A2 rs11854484 genotype, as well as the replicated association of ITPA and SLC28A3 genetic polymorphisms with RBV-induced anemia and treatment response, may support individualized treatment of chronic hepatitis C and warrant further investigation in larger studies.
|
23195617 |
2013 |