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rs6265
|
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|
0.100 |
GeneticVariation |
BEFREE |
This study has examined the association between the BDNF gene Val66Met polymorphism and mood disorders, age of onset and suicidal behavior in a Chinese sample population.
|
14673216 |
2003 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This study has examined the association between the BDNF gene Val66Met polymorphism and mood disorders, age of onset and suicidal behavior in a Chinese sample population.
|
14673216 |
2003 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.
|
15770238 |
2005 |
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rs759834365
|
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|
0.100 |
GeneticVariation |
BEFREE |
BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects.
|
15770238 |
2005 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This variant and two previously reported BDNF SNPs (C270T and Val66Met) were genotyped in 295 patients with AD, 108 with AFDs, 96 with posttraumatic stress disorder (PTSD), 84 with schizophrenia, 327 with alcohol and/or drug dependence, and 250 normal control subjects.
|
16649215 |
2006 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
This variant and two previously reported BDNF SNPs (C270T and Val66Met) were genotyped in 295 patients with AD, 108 with AFDs, 96 with posttraumatic stress disorder (PTSD), 84 with schizophrenia, 327 with alcohol and/or drug dependence, and 250 normal control subjects.
|
16649215 |
2006 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the present study, we evaluated the impact of the BDNF Val66Met polymorphism on individual differences in personality traits in a sample of healthy volunteers in relation to other common gene variants thought to be involved in the pathophysiology of affective disorders, such as the serotonin transporter promoter polymorphism (5-HTTLPR) and a variable number of tandem repeat polymorphism of the dopamine transporter gene (DAT VNTR).
|
17392738 |
2007 |
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rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In the present study, we evaluated the impact of the BDNF Val66Met polymorphism on individual differences in personality traits in a sample of healthy volunteers in relation to other common gene variants thought to be involved in the pathophysiology of affective disorders, such as the serotonin transporter promoter polymorphism (5-HTTLPR) and a variable number of tandem repeat polymorphism of the dopamine transporter gene (DAT VNTR).
|
17392738 |
2007 |
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rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Further investigations in larger samples are needed to clarify the usefulness of 5-HTTLPR and BDNF Val66Met genotyping in the optimization of non-pharmacological treatments in mood disorders.
|
18450378 |
2008 |
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rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Further investigations in larger samples are needed to clarify the usefulness of 5-HTTLPR and BDNF Val66Met genotyping in the optimization of non-pharmacological treatments in mood disorders.
|
18450378 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF gene: functional Val66Met polymorphism in mood disorders and schizophrenia.
|
19018714 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
BDNF gene: functional Val66Met polymorphism in mood disorders and schizophrenia.
|
19018714 |
2008 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Given that stress-induced atrophy of the hippocampus is associated with the pathogenesis of affective disorders, the functional BDNF Val66Met polymorphism could be an incremental risk factor.
|
19335934 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Given that stress-induced atrophy of the hippocampus is associated with the pathogenesis of affective disorders, the functional BDNF Val66Met polymorphism could be an incremental risk factor.
|
19335934 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Individuals with schizoaffective disorder and other affective disorders were significantly more likely to carry two copies of the most common BDNF haplotype (containing the valine allele of the Val66Met polymorphism) compared with healthy volunteers.
|
19336781 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Individuals with schizoaffective disorder and other affective disorders were significantly more likely to carry two copies of the most common BDNF haplotype (containing the valine allele of the Val66Met polymorphism) compared with healthy volunteers.
|
19336781 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Individuals at high risk of affective disorders and who are carriers of the met allele of the Val66Met polymorphism may present with an enhanced stress response.
|
19473771 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Individuals at high risk of affective disorders and who are carriers of the met allele of the Val66Met polymorphism may present with an enhanced stress response.
|
19473771 |
2009 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A polymorphism of the human Brain Derived Neurotrophic Factor (BDNF) gene that produces a valine-to-methionine substitution at codon 66 (Val66Met) is linked to adult anxiety and mood disorders, possibly through effects on brain circuitry function.
|
19931400 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A polymorphism of the human Brain Derived Neurotrophic Factor (BDNF) gene that produces a valine-to-methionine substitution at codon 66 (Val66Met) is linked to adult anxiety and mood disorders, possibly through effects on brain circuitry function.
|
19931400 |
2010 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The brain-derived neurotrophic factor (BDNF) Val(66) Met allelic variation is linked to both the occurrence of mood disorders and antidepressant response.
|
22225729 |
2012 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The brain-derived neurotrophic factor (BDNF) Val(66) Met allelic variation is linked to both the occurrence of mood disorders and antidepressant response.
|
22225729 |
2012 |
|
rs12273363
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study shows that the C allele of rs12273363, which is associated with mood disorder, modulates BP4 activity in an allele-specific manner following cell depolarization or the combined activity of protein kinase A and protein kinase C pathways.
|
22265241 |
2012 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The effect of the Val66Met polymorphism on synaptic transmission and plasticity in the IL-mPFC represents a mechanism to account for this impact of SNP on affective disorders and cognitive dysfunction.
|
22396415 |
2012 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The effect of the Val66Met polymorphism on synaptic transmission and plasticity in the IL-mPFC represents a mechanism to account for this impact of SNP on affective disorders and cognitive dysfunction.
|
22396415 |
2012 |