|
rs224278
|
|
C |
0.800 |
GeneticVariation |
GWASDB |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs224278
|
|
C |
0.800 |
GeneticVariation |
GWASCAT |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs4924410
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs4924410
|
|
A |
0.800 |
GeneticVariation |
GWASCAT |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs9430161
|
|
G |
0.800 |
GeneticVariation |
GWASCAT |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs9430161
|
|
G |
0.800 |
GeneticVariation |
GWASDB |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs12106193
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.
|
30093639 |
2018 |
|
rs6106336
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.
|
30093639 |
2018 |
|
rs7744366
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.
|
30093639 |
2018 |
|
rs7832583
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.
|
30093639 |
2018 |
|
rs11576658
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs2003046
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs8026641
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs944684
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
|
22327514 |
2012 |
|
rs752536342
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs772295894
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs231775
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we investigated the association of four CTLA-4 gene polymorphisms, -1661A/G (rs4553808), -318C/T (rs5742909), +49G/A (rs231775), and CT60A/G (rs3087243), with ES in the Chinese population.
|
23480667 |
2013 |
|
rs5742909
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we investigated the association of four CTLA-4 gene polymorphisms, -1661A/G (rs4553808), -318C/T (rs5742909), +49G/A (rs231775), and CT60A/G (rs3087243), with ES in the Chinese population.
|
23480667 |
2013 |
|
rs231775
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The current study evaluated the association of two CTLA-4 gene polymorphisms, -318C/T (rs5742909) and +49G/A (rs231775) with ES in the Chinese population.
|
22905924 |
2012 |
|
rs5742909
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The current study evaluated the association of two CTLA-4 gene polymorphisms, -318C/T (rs5742909) and +49G/A (rs231775) with ES in the Chinese population.
|
22905924 |
2012 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present meta-analysis, we aimed to elucidate the associations of TP53 rs1042522 genetic polymorphism with the risk of osteosarcoma or Ewing sarcoma.
|
30833364 |
2019 |
|
rs11188147
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also replicated associations with rs4148737 in the ATP-binding cassette subfamily B member 1 (ABCB1) gene (discovery: HR = 2.96, 95% CI = 1.08-8.10, P = 0.034; replication: HR = 1.60, 95% CI = 1.05-2.44, P = 0.029), which we have previously found to be associated with poorer OS in pediatric osteosarcoma patients, and rs11188147 in cytochrome P450 family 2 subfamily C member 8 gene (CYP2C8) (discovery : HR = 2.49, 95% CI = 1.06-5.87, P = 0.037; replication: HR = 1.77, 95% CI = 1.06-2.96, P = 0.030), an enzyme involved in the oxidative metabolism of the ES chemotherapeutic agents cyclophosphamide and ifosfamide.
|
27287205 |
2016 |
|
rs311059
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CD99 rs311059 T variant was found to be significantly associated [P value = 0.0029; ORhet = 3.9 (95% CI 1.5-9.8) and ORhom = 5.3 (95% CI 1.2-23.7)] with EWS onset in patients less than 14 years old, while the CD99 rs312257-T was observed to be associated [P value = 0.0265; ORhet = 3.5 (95% CI 1.3-9.9)] with a reduced risk of relapse.
|
27792997 |
2016 |
|
rs312257
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CD99 rs311059 T variant was found to be significantly associated [P value = 0.0029; ORhet = 3.9 (95% CI 1.5-9.8) and ORhom = 5.3 (95% CI 1.2-23.7)] with EWS onset in patients less than 14 years old, while the CD99 rs312257-T was observed to be associated [P value = 0.0265; ORhet = 3.5 (95% CI 1.3-9.9)] with a reduced risk of relapse.
|
27792997 |
2016 |
|
rs4148737
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We also replicated associations with rs4148737 in the ATP-binding cassette subfamily B member 1 (ABCB1) gene (discovery: HR = 2.96, 95% CI = 1.08-8.10, P = 0.034; replication: HR = 1.60, 95% CI = 1.05-2.44, P = 0.029), which we have previously found to be associated with poorer OS in pediatric osteosarcoma patients, and rs11188147 in cytochrome P450 family 2 subfamily C member 8 gene (CYP2C8) (discovery : HR = 2.49, 95% CI = 1.06-5.87, P = 0.037; replication: HR = 1.77, 95% CI = 1.06-2.96, P = 0.030), an enzyme involved in the oxidative metabolism of the ES chemotherapeutic agents cyclophosphamide and ifosfamide.
|
27287205 |
2016 |