DisGeNET - a database of gene-disease associations

Maternal hypertension, C0565599

Variant: rs1217691063 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1217691063

MTHFR

0.030

GeneticVariation

BEFREE

Several epidemiological studies have investigated the associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with hypertension (H) or hypertension in pregnancy (HIP).

24505291

2014

dbSNP:

rs1217691063

MTHFR

0.030

GeneticVariation

BEFREE

Strong association of methylenetetrahydrofolate reductase gene C677T polymorphism with hypertension and hypertension-in-pregnancy in Chinese: a meta-analysis.

21346782

2012

dbSNP:

rs1217691063

MTHFR

0.030

GeneticVariation

BEFREE

Meta-analysis of studies comparing women with and without hypertension in pregnancy for the C677T MTHFR polymorphism.

15311088

2004