Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1232880706
rs1232880706
FBN1
A 0.700 CausalMutation CLINVAR

dbSNP: rs1247665387
rs1247665387
FA2H
A 0.700 GeneticVariation CLINVAR

dbSNP: rs137854889
rs137854889
ZMPSTE24
GT 0.700 CausalMutation CLINVAR

dbSNP: rs1563183492
rs1563183492
AUTS2
T 0.700 GeneticVariation CLINVAR

dbSNP: rs61750420
rs61750420
PEX1
T 0.700 CausalMutation CLINVAR

dbSNP: rs66527965
rs66527965
COL1A1
T 0.700 CausalMutation CLINVAR

dbSNP: rs780533096
rs780533096
MIPEP
T 0.700 GeneticVariation CLINVAR

dbSNP: rs866294686
rs866294686
TRIM8 ; LOC105378460
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1217691063
rs1217691063
MTHFR
0.030 GeneticVariation BEFREE Several epidemiological studies have investigated the associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with hypertension (H) or hypertension in pregnancy (HIP). 24505291

2014
dbSNP: rs1217691063
rs1217691063
MTHFR
0.030 GeneticVariation BEFREE Strong association of methylenetetrahydrofolate reductase gene C677T polymorphism with hypertension and hypertension-in-pregnancy in Chinese: a meta-analysis. 21346782

2012
dbSNP: rs1217691063
rs1217691063
MTHFR
0.030 GeneticVariation BEFREE Meta-analysis of studies comparing women with and without hypertension in pregnancy for the C677T MTHFR polymorphism. 15311088

2004
dbSNP: rs699
rs699
AGT
0.030 GeneticVariation BEFREE We carried out association studies and multivariate analyses including other candidate causal factors of HP such as the M235T variant of the angiotensinogen (AGT) gene, prepregnancy body mass index (BMI), and family history of hypertension in Japanese subjects. 15042429

2004
dbSNP: rs699
rs699
AGT
0.030 GeneticVariation BEFREE The M235T variant of the angiotensinogen gene and the body mass index are useful markers for prevention of hypertension in pregnancy: a tree-based analysis of gene-environment interaction. 12536339

2002
dbSNP: rs699
rs699
AGT
0.030 GeneticVariation BEFREE To determine whether a state of hypertension in pregnancy in the Japanese can be predicted in the early period based on detection of the M235T variant of the angiotensinogen gene, alone or with other factors. 10586529

1999
dbSNP: rs2016347
rs2016347
IGF1R
0.010 GeneticVariation BEFREE Pregnancy Hypertension and a Commonly Inherited IGF1R Variant (rs2016347) Reduce Breast Cancer Risk by Enhancing Mammary Gland Involution. 31687025

2019
dbSNP: rs397507444
rs397507444
MTHFR
0.010 GeneticVariation BEFREE Several epidemiological studies have investigated the associations of methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with hypertension (H) or hypertension in pregnancy (HIP). 24505291

2014
dbSNP: rs11119982
rs11119982
ATF3
0.010 GeneticVariation BEFREE Gene-environment interactions were identified for rs523349 in SRD5A2 with estrogen exposure and maternal hypertension or preeclampsia, as well as for rs11119982 in ATF3 with exposure to cytokines. 23088992

2012
dbSNP: rs523349
rs523349
SRD5A2
0.010 GeneticVariation BEFREE Gene-environment interactions were identified for rs523349 in SRD5A2 with estrogen exposure and maternal hypertension or preeclampsia, as well as for rs11119982 in ATF3 with exposure to cytokines. 23088992

2012
dbSNP: rs2740574
rs2740574
CYP3A4
0.010 GeneticVariation BEFREE The CYP3A5 genotype was related with blood pressure in the general population, but the effect on the risk for hypertension in pregnancy has not been evaluated.We compared the allele and genotype frequencies of three functional SNPs in the CYP3A5 (rs776746), CYP3A4 (rs2740574), and CYP21A2 (rs6471) genes between pregnant women who developed hypertension (n = 250) or who remained normotensive (control group, n = 250). 20617557

2010
dbSNP: rs6471
rs6471
CYP21A2
0.010 GeneticVariation BEFREE The CYP3A5 genotype was related with blood pressure in the general population, but the effect on the risk for hypertension in pregnancy has not been evaluated.We compared the allele and genotype frequencies of three functional SNPs in the CYP3A5 (rs776746), CYP3A4 (rs2740574), and CYP21A2 (rs6471) genes between pregnant women who developed hypertension (n = 250) or who remained normotensive (control group, n = 250). 20617557

2010
dbSNP: rs776746
rs776746
CYP3A5 ; ZSCAN25
0.010 GeneticVariation BEFREE The CYP3A5 genotype was related with blood pressure in the general population, but the effect on the risk for hypertension in pregnancy has not been evaluated.We compared the allele and genotype frequencies of three functional SNPs in the CYP3A5 (rs776746), CYP3A4 (rs2740574), and CYP21A2 (rs6471) genes between pregnant women who developed hypertension (n = 250) or who remained normotensive (control group, n = 250). 20617557

2010
dbSNP: rs1695
rs1695
GSTP1
0.010 GeneticVariation BEFREE We therefore performed an association study of the Ile105Val variant comparing 131 patients with HP and 327 normal pregnant controls in Japan. 14719182

2003
dbSNP: rs370402227
rs370402227
NOS3
0.010 GeneticVariation BEFREE We therefore performed an association study of the Ile105Val variant comparing 131 patients with HP and 327 normal pregnant controls in Japan. 14719182

2003
dbSNP: rs1177506410
rs1177506410
AGT
0.010 GeneticVariation BEFREE We therefore performed an association study of the Glu298Asp variant with HP among 152 HP patients and 335 normal pregnant control individuals, in the context of other risk factors before pregnancy. 11745998

2001
dbSNP: rs1275805226
rs1275805226
AGT
0.010 GeneticVariation BEFREE We therefore performed an association study of the Glu298Asp variant with HP among 152 HP patients and 335 normal pregnant control individuals, in the context of other risk factors before pregnancy. 11745998

2001