Gene: PRNCR1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1456315
rs1456315
PCAT1 ; PRNCR1 ; CASC19
0.720 GeneticVariation BEFREE These included correlations between an intergenic CpG site at Chr8:128393157 and the prostate cancer SNP rs16902094 (ρ = -0.54; P = 9.7 × 10(-7); q = 0.002), a PRNCR1 CpG site at Chr8:128167809 and the prostate cancer SNP rs1456315 (ρ = 0.52; P = 1.4 × 10(-6); q = 0.002), and two POU5F1B CpG sites and several prostate/colorectal cancer SNPs (for Chr8:128498051 and rs6983267, ρ = 0.46; P = 2.0 × 10(-5); q = 0.01). 25315430

2014
dbSNP: rs13254738
rs13254738
PCAT1 ; PRNCR1 ; CASC19
0.720 GeneticVariation BEFREE The results of the meta-analyses indicate that rs6983267, rs1447295, rs6983561, rs7837688, rs16901979, and DG8S737 are significantly associated with a higher risk for PCa for at least one race, whereas the variants rs13254738 and rs7000448 are not. 22382457

2012
dbSNP: rs13254738
rs13254738
PCAT1 ; PRNCR1 ; CASC19
C 0.720 GeneticVariation GWASCAT Evaluating genetic risk for prostate cancer among Japanese and Latinos. 22923026

2012
dbSNP: rs1456315
rs1456315
PCAT1 ; PRNCR1 ; CASC19
0.720 GeneticVariation GWASCAT Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. 23023329

2012
dbSNP: rs1456315
rs1456315
PCAT1 ; PRNCR1 ; CASC19
0.720 GeneticVariation BEFREE Here, focusing on its most centromeric region (so-called Region 2: Chr8: 128.14-128.28 Mb) among the multiple PC loci on 8q24, we performed fine mapping and re-sequencing of this critical region and identified SNPs (single nucleotide polymorphisms) between rs1456315 and rs7463708 (chr8: 128,173,119-128,173,237 bp) to be most significantly associated with PC susceptibility (P = 2.00 × 10(-24) , OR = 1.74, 95% confidence interval = 1.56-1.93). 20874843

2011
dbSNP: rs1456315
rs1456315
PCAT1 ; PRNCR1 ; CASC19
0.720 GeneticVariation GWASCAT Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. 20676098

2010
dbSNP: rs13254738
rs13254738
PCAT1 ; PRNCR1 ; CASC19
0.720 GeneticVariation BEFREE This evidence of a protective effect for breast cancer of one variant (rs13254738) that has been associated previously with a 1.25-fold increased risk of prostate cancer, with no effect for the two other variants, indicates that the effects of the risk alleles clustered at 8q24 are cancer site specific. 18349290

2008
dbSNP: rs183373024
rs183373024
PCAT1 ; PRNCR1 ; CASC19
G 0.700 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016

2018
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs72725879
rs72725879
PCAT1 ; PRNCR1 ; CASC19
T 0.700 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies new prostate cancer susceptibility loci. 21743057

2011
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT Multiple newly identified loci associated with prostate cancer susceptibility. 18264097

2008
dbSNP: rs1016342
rs1016342
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
dbSNP: rs1016343
rs1016343
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
dbSNP: rs1031588
rs1031588
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
dbSNP: rs1551510
rs1551510
PCAT1 ; PRNCR1 ; CASC19 ; PCAT2
G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. 17401366

2007
dbSNP: rs16901946
rs16901946
PCAT1 ; PRNCR1 ; CASC19
0.010 GeneticVariation BEFREE Moreover, four prostate cancer-associated ncRNA 1 (PRNCR1, rs16901946 G/A, rs13252298 G/A, rs1016343 T/C, and rs1456315 G/A) SNPs were in association with cancer risk. 29802154

2018
dbSNP: rs7463708
rs7463708
PCAT1 ; PRNCR1 ; CASC19
0.010 GeneticVariation BEFREE Here, focusing on its most centromeric region (so-called Region 2: Chr8: 128.14-128.28 Mb) among the multiple PC loci on 8q24, we performed fine mapping and re-sequencing of this critical region and identified SNPs (single nucleotide polymorphisms) between rs1456315 and rs7463708 (chr8: 128,173,119-128,173,237 bp) to be most significantly associated with PC susceptibility (P = 2.00 × 10(-24) , OR = 1.74, 95% confidence interval = 1.56-1.93). 20874843

2011