In this study, 506 GC cases and 548 healthy controls (HCs) were collected to evaluate the association between the eleven SNPs (rs35220381, rs12950561, rs7221352, rs61482741, rs9303568, rs34700818, rs12949115, rs9903822, rs12601477, rs11656976 and rs4626) of the <i>TOB1</i> gene and GC risk in the population of northeast China.
The association between rs12601477 GA+AA genotypes and GC risk was significant among individuals older than 58 (adjusted OR=1.53, 95% CI=1.05-2.22, <i>P</i>< 0.05).
The results suggest that four SNPs (rs12601477, rs4626, rs34700818 and rs61482741) of the <i>TOB1</i> gene play an important role in the occurrence and development of GC in the Chinese Han population of northeast China.
The results suggest that four SNPs (rs12601477, rs4626, rs34700818 and rs61482741) of the <i>TOB1</i> gene play an important role in the occurrence and development of GC in the Chinese Han population of northeast China.
The results suggest that four SNPs (rs12601477, rs4626, rs34700818 and rs61482741) of the <i>TOB1</i> gene play an important role in the occurrence and development of GC in the Chinese Han population of northeast China.