Gene: ERCC4 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs744154
rs744154
ERCC4
0.020 GeneticVariation BEFREE Furthermore, the smokers with the rs744154 GC/CC genotypes showed a decreased risk of gastric cancer</span> (adjusted OR=0.55, 95% CI=0.35-0.85) compared with the smokers with the GG genotype using multivariate LR analysis. 23537993

2013
dbSNP: rs744154
rs744154
ERCC4
0.020 GeneticVariation BEFREE A non-significant increased risk of gastric cancer was found in individuals carrying the rs744154 GG genotype. 23679285

2013
dbSNP: rs2020959
rs2020959
ERCC4
0.010 GeneticVariation BEFREE As the C2169A mutation is closely associated with gastric carcinogenesis in the Chinese population, our findings shine light on it as a therapeutic target for early diagnosis and treatment of gastric cancer. 24412486

2014
dbSNP: rs2276465
rs2276465
ERCC4
0.010 GeneticVariation BEFREE We found that the XPF rs6498486 and XPF rs2276465 polymorphisms are mark-ers of response to oxaliplatin/5-fluorouracil-based chemotherapy in gastric cancer patients. 25222248

2014
dbSNP: rs1799801
rs1799801
ERCC4
0.010 GeneticVariation BEFREE Our study indicated that polymorphisms in rs180067, rs1799801, rs2276466 and rs744154 may affect the risk of gastric cancer but further large sample size studies are needed to validate any association. 23679285

2013
dbSNP: rs2276466
rs2276466
ERCC4
0.010 GeneticVariation BEFREE Our study indicated that polymorphisms in rs180067, rs1799801, rs2276466 and rs744154 may affect the risk of gastric cancer but further large sample size studies are needed to validate any association. 23679285

2013
dbSNP: rs254942
rs254942
ERCC4
0.010 GeneticVariation BEFREE Thereby, we investigated the association between two tag single nucleotide polymorphisms (tagSNPs) rs6498486 and rs254942, which represents the majority of common SNPs of ERCC4 gene, and the risks of GC and AG development in a sex- and age-matched case-control designed study. 23415627

2013
dbSNP: rs6498486
rs6498486
ERCC4
0.010 GeneticVariation BEFREE Only rs6498486 AC and AC/CC genotypes were found to be marginally associated with a reduced GC risk in the subgroup of males (for AC vs. AA: OR=0.69, 95%CI=0.49-0.99, P=0.043; for AC/CC vs. AA: OR=0.71, 95%CI=0.50-0.99, P=0.046). 23415627

2013