rs28934576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Various human p53 mutants (V143A, V173L, H179Q, N247I and R273H) were introduced to the TCC-SUP bladder carcinoma cell line to establish stable transfectants.
|
11435891 |
2001 |
rs1695
|
|
|
0.080 |
GeneticVariation |
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
rs768623239
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We investigated the effect of the GSTM1 and GSTT1 null genotypes, and GSTP1 313 A/G polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients, and 121 age- and sex-matched controls of the Turkish population.
|
11757669 |
2001 |
rs2066853
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To assess two polymorphic forms of aryl hydrocarbon receptor (AHR) gene, G1721A (R554K), and G1768A (V570I) in Chinese population and to explore the possible association of human AHR gene polymorphism with elevated incidence of bladder cancer among Chinese Han subjects in east of China.
|
11866883 |
2002 |
rs4986826
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To assess two polymorphic forms of aryl hydrocarbon receptor (AHR) gene, G1721A (R554K), and G1768A (V570I) in Chinese population and to explore the possible association of human AHR gene polymorphism with elevated incidence of bladder cancer among Chinese Han subjects in east of China.
|
11866883 |
2002 |
rs1042028
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Because of its functional role and published data showing the influence of Arg213His polymorphism on the risk of some cancers, we hypothesized that the His(213) allele of the SULT1A1 gene may modify bladder cancer risk.
|
14643027 |
2003 |
rs9282861
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Because of its functional role and published data showing the influence of Arg213His polymorphism on the risk of some cancers, we hypothesized that the His(213) allele of the SULT1A1 gene may modify bladder cancer risk.
|
14643027 |
2003 |
rs1805087
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We investigated joint effects of polymorphisms of the MTHFR (677 C-->T, 1298A-->C) and MS genes (2756 A-->G), dietary folate intake and cigarette smoking on the risk of bladder cancer in a case-control study.
|
15117811 |
2004 |
rs1043210477
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The GPX1 Pro/Leu genotype may significantly increase the risk of bladder cancer and the increased risk may be modified by the Ala-9Val MnSOD polymorphism.
|
15247771 |
2004 |
rs953038635
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The GPX1 Pro/Leu genotype may significantly increase the risk of bladder cancer and the increased risk may be modified by the Ala-9Val MnSOD polymorphism.
|
15247771 |
2004 |
rs121909218
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To address these issues, we stably transfected several commonly used human bladder cancer cell lines with known invasive phenotypes with either wild-type PTEN constructs or those deficient in the lipid phosphatase (G129E) or both protein and lipid phosphatase (G129R) activities.
|
15273733 |
2004 |
rs786204929
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To address these issues, we stably transfected several commonly used human bladder cancer cell lines with known invasive phenotypes with either wild-type PTEN constructs or those deficient in the lipid phosphatase (G129E) or both protein and lipid phosphatase (G129R) activities.
|
15273733 |
2004 |
rs25487
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our data are consistent with a potential role of the XRCC1 Arg399Gln polymorphism in bladder cancer susceptibility and further suggest that there may be DNA lesions important in bladder carcinogenesis, repaired by the base excision repair mechanism, that are not directly associated with tobacco smoking.
|
15298955 |
2004 |
rs2074647
|
|
|
0.010 |
GeneticVariation |
BEFREE |
When the SNPs were analyzed separately, the RGS6-rs2074647 (C-->T) polymorphism conferred the greatest overall reduction in risk of bladder cancer (odds ratio, 0.66; 95% confidence interval, 0.46-0.95).
|
15375002 |
2004 |
rs386675647
|
|
|
0.020 |
GeneticVariation |
BEFREE |
An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China.
|
15615884 |
2005 |
rs7439366
|
|
|
0.020 |
GeneticVariation |
BEFREE |
An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China.
|
15615884 |
2005 |
rs765502022
|
|
|
0.020 |
GeneticVariation |
BEFREE |
An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China.
|
15615884 |
2005 |
rs1287276985
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GSTM1-negative, GSTT1-positive, and hOGG1 Ser326Ser and Ser326Cys genotypes are risk factors for bladder cancer (P = 0.020, P = 0.044, and P = 0.012, respectively).
|
15667866 |
2005 |
rs758272654
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The T393C polymorphism of the G alpha s gene (GNAS1) is a novel prognostic marker in bladder cancer.
|
15824158 |
2005 |
rs12917
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We hypothesized that two MGMT polymorphisms in exon 3, C16195T (or MGMT L53L) and C16286T (or MGMT L84F) are associated with risk of bladder cancer.
|
15885889 |
2005 |
rs2228001
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Using logistic regression adjusting for smoking, occupational and family history, neither the heterozygote nor the homozygote variants of these polymorphisms were associated with increased bladder cancer risk (adjusted odds ratio [95% confidence interval] for heterozygote 0.82 [0.63-1.07], 0.82 [0.63-1.08] and 0.83 [0.63-1.08] for PolyAT, IVS11-6 and Lys939Gln, respectively and homozygote variant, 0.98 [0.68-1.42], 0.99 [0.69-1.43] and 1.01 [0.70-1.46]).
|
15886698 |
2005 |
rs1041983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate whether the slow acetylator genotype is a risk factor for development of bladder cancer following schistosomal infection of the urinary tract, the authors determined the frequencies of 3 common polymorphisms in the NAT2 gene (341T>C, 590G>A, and 282C>T), which are associated with impaired acetylation activity, in control subjects (n=61; mean age 34.3+/-9.2 years) and in schistosomiasis-associated bladder cancer patients (n=55; 52+/-10.9 years) from the Egyptian population.
|
15905799 |
2005 |
rs1801280
|
|
|
0.010 |
GeneticVariation |
BEFREE |
NAT2*5/*5 genotype (341T>C) is a potential risk factor for schistosomiasis-associated bladder cancer in Egyptians.
|
15905799 |
2005 |
rs758272654
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have recently shown an association between the GNAS1 T393C polymorphism and disease progression in patients with bladder cancer with homozygous TT genotypes displaying increased transcription of Galpha s and a more favorable clinical course compared with C-allele carriers.
|
16033819 |
2005 |
rs1801282
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using the TaqMan method, we genotyped single nucleotide polymorphisms in interleukin (IL) -6 (-174 G-->C), IL-8 (-251 T-->A), tumor necrosis factor-alpha (TNF-alpha; -308 G-->A), and peroxisome proliferator-activated receptor gamma (PPARG; Pro12Ala), and determined their associations with BC initiation and clinical outcome.
|
16110031 |
2005 |