|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
<b>Results</b> We found that the early pregnancy loss (EPL) rate increased as MTHFR polymorphism complexity increased and that the early EPL rate was significantly higher in patients with MTHFR C677T polymorphism compared to patients with MTHFR A1298C polymorphism (p = 0.039).
|
30258247 |
2018 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
MTHFR C677T polymorphism and recurrent early pregnancy loss risk in north Indian population.
|
22138544 |
2012 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The methylenetetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms are commonly associated with defects in folate dependent homocysteine metabolism and have been implicated as risk factors for recurrent embryo loss in early pregnancy.
|
11938441 |
2002 |
|
rs1217691063
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Because of MTHFR's involvement with folate metabolism and evidence that maternal use of a multivitamin with folic acid in early pregnancy reduces risk for cleft lip with or without cleft palate (CLP), we hypothesized that infants homozygous for the C677T genotype would be at increased risk for CLP because of lower MTHFR enzymatic activity.
|
9843036 |
1998 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
<b>Results</b> We found that the early pregnancy loss (EPL) rate increased as MTHFR polymorphism complexity increased and that the early EPL rate was significantly higher in patients with MTHFR C677T polymorphism compared to patients with MTHFR A1298C polymorphism (p = 0.039).
|
30258247 |
2018 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The methylenetetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms are commonly associated with defects in folate dependent homocysteine metabolism and have been implicated as risk factors for recurrent embryo loss in early pregnancy.
|
11938441 |
2002 |
|
rs1569686
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the growing evidence on the important roles of DNA methylation in gametogenesis and early pregnancy, we investigated the potential association of DNA methyltransferase gene polymorphisms (DNMT1 rs2228611, DNMT3A rs1550117, DNMT3B rs1569686) with RSA in Slovenian reproductive couples.
|
28940947 |
2017 |
|
rs2228611
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Considering the growing evidence on the important roles of DNA methylation in gametogenesis and early pregnancy, we investigated the potential association of DNA methyltransferase gene polymorphisms (DNMT1 rs2228611, DNMT3A rs1550117, DNMT3B rs1569686) with RSA in Slovenian reproductive couples.
|
28940947 |
2017 |
|
rs117106081
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, PROKR1 (I379V) and PROKR2 (V331M) variants conferred lower risk for RM and may play protective roles in early pregnancy by altering calcium signaling and facilitating cell invasiveness.
|
23687280 |
2013 |
|
rs1421868342
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, PROKR1 (I379V) and PROKR2 (V331M) variants conferred lower risk for RM and may play protective roles in early pregnancy by altering calcium signaling and facilitating cell invasiveness.
|
23687280 |
2013 |
|
rs34715748
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, PROKR1 (I379V) and PROKR2 (V331M) variants conferred lower risk for RM and may play protective roles in early pregnancy by altering calcium signaling and facilitating cell invasiveness.
|
23687280 |
2013 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results do not show any influence of the two polymorphisms, VNTR in intron 4 and Glu298Asp of the eNOS gene, on early pregnancy.
|
18299866 |
2008 |