Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2910164
rs2910164
0.020 GeneticVariation BEFREE The results indicate that the miR-146a rs2910164 polymorphism was significantly associated with increased risk of digestive system cancer in heterozygote comparison (GC vs. CC: OR=1.15, 95% CI: 1.02-1.30, P=0.02), and recessive model (GG vs. GC+CC: OR=1.11, 95% CI: 1.04-1.17, P=0.006). 27477122

2017

dbSNP: rs2910164
rs2910164
0.020 GeneticVariation BEFREE This current meta-analysis indicated that miR-146a rs2910164 polymorphism may decrease the susceptibility to digestive system cancers, especially in Asian populations. 24528016

2014

dbSNP: rs4919510
rs4919510
0.010 GeneticVariation BEFREE Overall, no significant association was found between microRNA-608 rs4</span>919510 G>C polymorphism and DSCs risk in general populations. 29930517

2018

dbSNP: rs2279115
rs2279115
0.010 GeneticVariation BEFREE Furthermore, rs2279115 was associated with a significantly higher risk in digestive system cancer and endocrine system cancer but not in breast cancer, respiratory cancer and hematopoietic cancer. 28445963

2017

dbSNP: rs712
rs712
0.010 GeneticVariation BEFREE In summary, these evidences demonstrate that let-7-KRAS rs712 G > T polymorphism might be associated with digestive system cancer risk in the Chinese population. 28099923

2017

dbSNP: rs1052133
rs1052133
0.010 GeneticVariation BEFREE In our analysis, the hOGG1 Ser326Cys polymorphism was significantly associated with the risk of digestive system cancers (Cys/Cys vs. Ser/Ser: OR = 1.17, 95% CI = 1.00-1.35, P < 0.001; Cys/Cys vs. Cys/Ser + Ser/Ser: OR = 1.14, 95% CI = 1.00-1.29, P < 0.001). 25323581

2015

dbSNP: rs11549465
rs11549465
0.010 GeneticVariation BEFREE HIF-1α P582S and A588T polymorphisms and digestive system cancer risk-a meta-analysis. 24293391

2014

dbSNP: rs11549467
rs11549467
0.010 GeneticVariation BEFREE HIF-1α P582S and A588T polymorphisms and digestive system cancer risk-a meta-analysis. 24293391

2014

dbSNP: rs1805794
rs1805794
NBN
0.010 GeneticVariation BEFREE Notably, the Glu185Gln polymorphism was found to be related to increased risk for urinary system cancer, but decreased risk for digestive system cancer. 23979977

2014

dbSNP: rs187084
rs187084
0.010 GeneticVariation BEFREE In conclusion, our results suggest that the rs187084 polymorphism may be associated with an elevated cancer risk, whereas polymorphisms of rs352140 and rs5743836 may play protective roles in the development of breast and digestive system cancers, respectively. 25339018

2014

dbSNP: rs2010963
rs2010963
0.010 GeneticVariation BEFREE VEGF +405G/C (rs2010963) polymorphisms and digestive system cancer risk: a meta-analysis. 24474253

2014

dbSNP: rs352140
rs352140
0.010 GeneticVariation BEFREE In conclusion, our results suggest that the rs187084 polymorphism may be associated with an elevated cancer risk, whereas polymorphisms of rs352140 and rs5743836 may play protective roles in the development of breast and digestive system cancers, respectively. 25339018

2014

dbSNP: rs5743836
rs5743836
0.010 GeneticVariation BEFREE In conclusion, our results suggest that the rs187084 polymorphism may be associated with an elevated cancer risk, whereas polymorphisms of rs352140 and rs5743836 may play protective roles in the development of breast and digestive system cancers, respectively. 25339018

2014

dbSNP: rs1805087
rs1805087
MTR
0.010 GeneticVariation BEFREE This meta-analysis suggests that there is no significant association between the MTR A2756G polymorphism and digestive system cancer risk. 23613867

2013

dbSNP: rs4986791
rs4986791
0.010 GeneticVariation BEFREE However, no significant association with risk of digestive system cancers was observed for TLR2 -196 to -174 del and TLR4 rs4986791. 24376595

2013

dbSNP: rs11614913
rs11614913
0.010 GeneticVariation BEFREE The association between single nucleotide polymorphism (SNP) in miR-196a2 rs11614913 and the susceptibility of digestive system cancers was inconsistent in previous studies. 22291993

2012