|
rs1805794
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Despite some limitations, this meta-analysis established some solid statistical evidence for the association between NBS1 Glu185Gln polymorphism and increased risk for urinary system cancer, especially for bladder cancer, but more well-designed prospective studies are needed to further verify our findings.
|
25073514 |
2014 |
|
rs1805794
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Notably, the Glu185Gln polymorphism was found to be related to increased risk for urinary system cancer, but decreased risk for digestive system cancer.
|
23979977 |
2014 |
|
rs11614913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that CT (miR-196a2, C>T rs11614913) was a risk factor for renal cell carcinoma (CT vs. CC: OR = 1.72, 95%CI = 1.05-2.80, <i>P</i> = 0.03, <i>I</i><sup>2</sup> = 66%), especially in Asian population (CT vs. CC: OR = 1.17, 95%CI = 1.04-1.32, <i>P</i> < 0.01, <i>I</i><sup>2</sup> = 0%). miR-146a G>C rs2910164 was a protective factor of urological cancers (C vs. G: OR = 0.87, 95%CI = 0.81-0.93, <i>P</i> < 0.01, <i>I</i><sup>2</sup> = 0%), especially for bladder cancer. miR-499 A>G rs3746444 was correlated with an increased risk of urological cancers, specifically in Asian population.
|
28579964 |
2017 |
|
rs2910164
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that CT (miR-196a2, C>T rs11614913) was a risk factor for renal cell carcinoma (CT vs. CC: OR = 1.72, 95%CI = 1.05-2.80, <i>P</i> = 0.03, <i>I</i><sup>2</sup> = 66%), especially in Asian population (CT vs. CC: OR = 1.17, 95%CI = 1.04-1.32, <i>P</i> < 0.01, <i>I</i><sup>2</sup> = 0%). miR-146a G>C rs2910164 was a protective factor of urological cancers (C vs. G: OR = 0.87, 95%CI = 0.81-0.93, <i>P</i> < 0.01, <i>I</i><sup>2</sup> = 0%), especially for bladder cancer. miR-499 A>G rs3746444 was correlated with an increased risk of urological cancers, specifically in Asian population.
|
28579964 |
2017 |
|
rs3746444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that CT (miR-196a2, C>T rs11614913) was a risk factor for renal cell carcinoma (CT vs. CC: OR = 1.72, 95%CI = 1.05-2.80, <i>P</i> = 0.03, <i>I</i><sup>2</sup> = 66%), especially in Asian population (CT vs. CC: OR = 1.17, 95%CI = 1.04-1.32, <i>P</i> < 0.01, <i>I</i><sup>2</sup> = 0%). miR-146a G>C rs2910164 was a protective factor of urological cancers (C vs. G: OR = 0.87, 95%CI = 0.81-0.93, <i>P</i> < 0.01, <i>I</i><sup>2</sup> = 0%), especially for bladder cancer. miR-499 A>G rs3746444 was correlated with an increased risk of urological cancers, specifically in Asian population.
|
28579964 |
2017 |
|
rs1253195913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
All five mutations are associated with NS, whereas two (A57G and F82V) have also been identified in urinary tract cancers and myeloid malignancies.
|
27226556 |
2016 |
|
rs1801157
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, we confirmed that the SDF-1 rs1801157 gene polymorphism was only associated with lung and urologic cancer risk.
|
27265091 |
2016 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although we could not detect a positive function of the COMT Val158Met polymorphism in urological cancers, the polymorphism might be significantly associated with bladder cancer risk (dominant model [AA + AG vs. GG]: OR = 0.736, 95% CI = 0.586-0.925, I2 = 0.00%; recessive model [AA vs. AG + GG]: OR = 0.822, 95%CI = 0.653-1.035, I2 = 6.30%; codominant model [AA vs. AG]: OR = 0.908, 95% CI = 0.710-1.161, I2 = 0.00%; codominant model [AA vs. GG]: OR = 0.693, 95% CI = 0.524-0.917, I2 = 30.20%; allele analysis [A vs. G]: OR = 0.826, 95%CI = 0.717-0.951, I2 = 30.20%).
|
27055785 |
2016 |
|
rs672601334
|
|
|
0.010 |
GeneticVariation |
BEFREE |
All five mutations are associated with NS, whereas two (A57G and F82V) have also been identified in urinary tract cancers and myeloid malignancies.
|
27226556 |
2016 |
|
rs869025194
|
|
|
0.010 |
GeneticVariation |
BEFREE |
All five mutations are associated with NS, whereas two (A57G and F82V) have also been identified in urinary tract cancers and myeloid malignancies.
|
27226556 |
2016 |
|
rs1258159645
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, significant association was found between NQO1 Pro1</span>87Ser polymorphism and urinary system cancer risk.
|
25608636 |
2015 |
|
rs1800566
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, significant association was found between NQO1 Pro1</span>87Ser polymorphism and urinary system cancer risk.
|
25608636 |
2015 |