Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs25531
rs25531
0.020 GeneticVariation BEFREE When reflecting on the separation, self-reported psychological distress following the separation interacted with a polymorphism in the serotonin transporter gene (5-HTTLPR) and a relevant single nucleotide polymorphism (SNP), rs25531, to predict RSA. 25630596

2015

dbSNP: rs25531
rs25531
0.020 GeneticVariation BEFREE Findings suggest that 5-HTTLPR/rs25531 genotype is associated with psychological distress in a sample of subjects with diabetes. 22921508

2012

dbSNP: rs12673132
rs12673132
0.010 GeneticVariation BEFREE The NPSR1 polymorphisms rs12673132 significantly affected the relationship of somatization with psychological distress (p < 0.05). 30616163

2019

dbSNP: rs4680
rs4680
0.010 GeneticVariation BEFREE To examine the association of the COMT val(158)met variant with personality traits (harm avoidance, novelty seeking, reward dependence, resilience) and psychological distress (K10) of habitual physically active Ironman athletes compared to recreationally active controls. 26253211

2015

dbSNP: rs1051730
rs1051730
0.010 GeneticVariation BEFREE In Mendelian randomisation analyses, there was no strong evidence that the minor allele of rs16969968/rs1051730 was associated with depression (OR=1.00, 95% CI 0.95 to 1.05), anxiety (OR=1.02, 95% CI 0.97 to 1.07) or psychological distress (OR=1.02, 95% CI 0.98 to 1.06) in current smokers. 25293386

2014

dbSNP: rs16969968
rs16969968
0.010 GeneticVariation BEFREE In Mendelian randomisation analyses, there was no strong evidence that the minor allele of rs16969968/rs1051730 was associated with depression (OR=1.00, 95% CI 0.95 to 1.05), anxiety (OR=1.02, 95% CI 0.97 to 1.07) or psychological distress (OR=1.02, 95% CI 0.98 to 1.06) in current smokers. 25293386

2014

dbSNP: rs1325757098
rs1325757098
0.010 GeneticVariation BEFREE There was evidence of a potential association between BDNF (Val66Met) and psychological distress. 22652301

2013

dbSNP: rs6265
rs6265
0.010 GeneticVariation BEFREE There was evidence of a potential association between BDNF (Val66Met) and psychological distress. 22652301

2013

dbSNP: rs759834365
rs759834365
0.010 GeneticVariation BEFREE There was evidence of a potential association between BDNF (Val66Met) and psychological distress. 22652301

2013

dbSNP: rs2478813
rs2478813
0.010 GeneticVariation BEFREE There was evidence of an allelic association between rs2478813 (and other single nucleotide polymorphisms correlated with it) and anxiety, depression, neuroticism, and psychological distress; the association with anxiety is significant after Bonferroni correction for multiple testing (empirical P<.001). 17339520

2007

dbSNP: rs716461
rs716461
0.010 GeneticVariation BEFREE To perform a genetic association study between 6 single nucleotide polymorphisms from the PLXNA2 gene (rs3736963, rs2767565, rs752016, rs1327175, rs2478813, and rs716461) and anxiety, depression, neuroticism, and psychological distress. 17339520

2007