|
rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We further observed enrichment of the hOGG1 Ser326Cys polymorphism in the CIN III (p = 0.021) and CSCC (p < 0.001) stratified by age at first intercourse, with more significant enrichment (p = 0.036) in the HR-HPV infection group.
|
30648893 |
2019 |
|
rs10851465
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No correlations were found between four DUT SNPs (rs3784621, rs10851465, rs28381106 and rs28381126) and CIN III and CSCC risk.
|
30679536 |
2019 |
|
rs11637235
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, these findings suggested that the homozygous GG allele of rs3784619 and the TT allele of rs11637235 in the DUT gene significantly increased the risk of CIN III and CSCC.
|
30679536 |
2019 |
|
rs2029167
|
|
|
0.010 |
GeneticVariation |
BEFREE |
During the linkage disequilibrium analysis between rs3087404 (A/G) and rs2029167 (A/G), the genotype with AA-GG [OR=3.14(1.95-5.05)], AG-GG [OR=2.45(1.58-3.89)], GG-AA [OR=2.24(1.28-3.90)] and GG-AG [OR=2.58(1.54-4.32)] significantly increased the risk of CIN III.
|
30662544 |
2019 |
|
rs28381106
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No correlations were found between four DUT SNPs (rs3784621, rs10851465, rs28381106 and rs28381126) and CIN III and CSCC risk.
|
30679536 |
2019 |
|
rs28381126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No correlations were found between four DUT SNPs (rs3784621, rs10851465, rs28381106 and rs28381126) and CIN III and CSCC risk.
|
30679536 |
2019 |
|
rs3087404
|
|
|
0.010 |
GeneticVariation |
BEFREE |
During the linkage disequilibrium analysis between rs3087404 (A/G) and rs2029167 (A/G), the genotype with AA-GG [OR=3.14(1.95-5.05)], AG-GG [OR=2.45(1.58-3.89)], GG-AA [OR=2.24(1.28-3.90)] and GG-AG [OR=2.58(1.54-4.32)] significantly increased the risk of CIN</span> III.
|
30662544 |
2019 |
|
rs3784619
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, these findings suggested that the homozygous GG allele of rs3784619 and the TT allele of rs11637235 in the DUT gene significantly increased the risk of CIN III and CSCC.
|
30679536 |
2019 |
|
rs246079
|
|
|
0.010 |
GeneticVariation |
BEFREE |
At the UNG rs246079</span> (A/G) locus, individuals with the G allele or G carrier (GG + AG) genotype were at higher risk for CIN III (OR = 1.34) and CSCC (OR = 1.55).
|
30572497 |
2018 |
|
rs3219218
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed no association between the UNG rs3219218 (A/G) polymorphism and risk of CIN III or CSCC.
|
30572497 |
2018 |
|
rs2305809
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The single most significant SNPs from each gene associated with CIN3/cancer were PRDX3 rs7082598 (P(trend)<0.0001), and RPS19 rs2305809 (P(trend)=0.0007), respectively.
|
22496757 |
2012 |
|
rs7082598
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The single most significant SNPs from each gene associated with CIN3/cancer were PRDX3 rs7082598 (P(trend)<0.0001), and RPS19 rs2305809 (P(trend)=0.0007), respectively.
|
22496757 |
2012 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated 11 SNPs, including Pro72Arg (rs1042522), among 1,281 women: 465 with cervical intraepithelial neoplasia grade 3/cancer (CIN3+), 380 with HPV persistence (median, 25 months), and 436 random population controls.
|
19423538 |
2009 |
|
rs1131691014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated 11 SNPs, including Pro72Arg (rs1042522), among 1,281 women: 465 with cervical intraepithelial neoplasia grade 3/cancer (CIN3+), 380 with HPV persistence (median, 25 months), and 436 random population controls.
|
19423538 |
2009 |
|
rs1280759302
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The odds ratios (OR) for CIN III were significantly lower among carriers of the TAP1 I333V polymorphism (OR, 0.28; 95% confidence interval, 0.1-0.8), and TAP1 D637G polymorphism (OR, 0.27; 95% confidence interval, 0.1-0.7).
|
19188174 |
2009 |
|
rs750898115
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The odds ratios (OR) for CIN III were significantly lower among carriers of the TAP1 I333V polymorphism (OR, 0.28; 95% confidence interval, 0.1-0.8), and TAP1 D637G polymorphism (OR, 0.27; 95% confidence interval, 0.1-0.7).
|
19188174 |
2009 |
|
rs878854066
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated 11 SNPs, including Pro72Arg (rs1042522), among 1,281 women: 465 with cervical intraepithelial neoplasia grade 3/cancer (CIN3+), 380 with HPV persistence (median, 25 months), and 436 random population controls.
|
19423538 |
2009 |
|
rs587782329
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Neither specific HPV-16 350G/T variants nor specific p53 genotypes were associated with a higher risk of developing CIN III or cervical cancer.
|
10644829 |
2000 |