rs4073
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The T allele of rs4073 was significantly over-represented in suicide attempt group compared with both control and completed suicide groups (adjusted P values of 8.3E-7 and 9.8E-8 respectively).
|
30099207 |
2018 |
rs4307059
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The CC genotype of rs4307059 located in the region between CDH9 and CDH10 is associated with completed suicide in a Polish cohort.
|
22846907 |
2012 |
rs6295
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In humans, the G variant of the C(-1019)G 5-HT1A receptor promoter gene polymorphism (rs6295) has been associated with higher expression of 5-HT1A receptors, increased depression, and lower stress preceding completed suicide.
|
21397953 |
2011 |
rs6943555
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We hypothesized that rs6943555 might be associated with completed suicide.
|
23437340 |
2013 |
rs7124442
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis (rs7124442-rs10767664-rs962369-rs12273363-rs908867) showed an association of the haplotype C-A-T-C-C (p(corr)=0.038) with completed suicide, indicating that these SNPs on a haplotype level may play a role in completed suicide phenotype in our study sample.
|
26115627 |
2015 |
rs734312
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The nonsynonymous variants rs1383180 in EVC gene, rs6811863 in TBC1D1 gene, rs362272 in HTT gene, and rs734312 in WFS1 gene were associated to the male completed suicide.
|
19115052 |
2009 |
rs745918508
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, additional association tests yielded four significant PsychArray variants (SP110, rs181058279; AGBL2, rs76215382; SUCLA2, rs121908538; APH1B, rs745918508), raising the likelihood that these genes confer risk of completed suicide.
|
30353169 |
2018 |
rs759834365
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The meta-analyses of the valine with methionine in codon 66 (Val66Met) single nucleotide polymorphism (SNP) showed that the Met-allele tended to be associated with attempted suicide in Asian populations, but not with the completed suicide.
|
23850432 |
2013 |
rs76215382
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, additional association tests yielded four significant PsychArray variants (SP110, rs181058279; AGBL2, rs76215382; SUCLA2, rs121908538; APH1B, rs745918508), raising the likelihood that these genes confer risk of completed suicide.
|
30353169 |
2018 |
rs821616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The functional Ser704Cys variant of DISC1 was nominally associated with completed suicide.
|
24289909 |
2014 |
rs908867
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis (rs7124442-rs10767664-rs962369-rs12273363-rs908867) showed an association of the haplotype C-A-T-C-C (p(corr)=0.038) with completed suicide, indicating that these SNPs on a haplotype level may play a role in completed suicide phenotype in our study sample.
|
26115627 |
2015 |
rs930752
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We hypothesized that DNA variants affecting neurodevelopment such as rs4307059 (CDH10/CDH9), rs930752 (NRXN1), rs6265 (BDNF) or rs10868235 (NTRK2) may predispose to completed suicide.
|
22846907 |
2012 |
rs9393
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We used three high-frequency SNPs (rs1532976, rs3752826, and rs9393) and found a significant association of two alleles (rs1532976 and rs3752826) with completed suicide (p < 0.05).
|
15838597 |
2005 |
rs962369
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Haplotype analysis (rs7124442-rs10767664-rs962369-rs12273363-rs908867) showed an association of the haplotype C-A-T-C-C (p(corr)=0.038) with completed suicide, indicating that these SNPs on a haplotype level may play a role in completed suicide phenotype in our study sample.
|
26115627 |
2015 |
rs9939609
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our study proves that there is an inverse association between rs9939609 polymorphism in FTO gene and completed suicide which is independent from association between FTO and alcohol addiction.
|
25265168 |
2014 |