Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE Polymorphism in the methylenetetrahydrofolate reductase (C677T) gene and homocysteine levels: a comparison in Brazilian patients with coronary arterial disease, ischemic stroke and peripheral arterial obstructive disease. 18040753

2009
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE Our TDT analysis clearly demonstrates a lack of association between the T allele of the C677T mutation in MTHFR and cardiovascular artery disease, both for the general group and for different risk subgroups (smokers, hypertension, male sex, overweight and type A behaviour pattern) in the Spanish population. 12220440

2002
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE However, the results of most of the previous studies suggest that the C677T MTHFR mutation is not a significant risk factor for arterial disease. 10360632

1999
dbSNP: rs1217691063
rs1217691063
MTHFR
0.040 GeneticVariation BEFREE C677T substitution in the methylenetetrahydrofolate reductase gene as a risk factor for venous thrombosis and arterial disease in selected patients. 10477457

1999
dbSNP: rs387906592
rs387906592
ACTA2 ; STAMBPL1
0.020 GeneticVariation BEFREE Cerebral arteriopathy associated with Arg179His ACTA2 mutation. 24353327

2014
dbSNP: rs387906592
rs387906592
ACTA2 ; STAMBPL1
0.020 GeneticVariation BEFREE Cerebral arteriopathy associated with Arg179His ACTA2 mutation. 24293535

2013
dbSNP: rs1800976
rs1800976
ABCA1 ; LOC105376196
0.010 GeneticVariation BEFREE Abnormal left ventricular size and left-artery disease correlated with rs2422493-T and rs1800976-G alleles, respectively. 31150543

2020
dbSNP: rs2422493
rs2422493
ABCA1 ; LOC105376196
0.010 GeneticVariation BEFREE Abnormal left ventricular size and left-artery disease correlated with rs2422493-T and rs1800976-G alleles, respectively. 31150543

2020
dbSNP: rs77375493
rs77375493
JAK2 ; INSL6
0.010 GeneticVariation BEFREE The current study describes rare cases of SAH accompanied by ischemic stroke secondary to ET along with a review of the current literature, implying specific mechanisms for cerebral artery disorders associated with JAK2 V617F mutation. 31049728

2019
dbSNP: rs14035
rs14035
RAN
0.010 GeneticVariation BEFREE In multivariate Cox proportional hazard regression models, a significant association was found between <i>RAN</i> rs14035 and survival of large artery disease patients with ischemic stroke (CC vs. TT: adjusted hazard ratio, 5.978; <i>P</i>=0.015). 29402068

2018
dbSNP: rs11053646
rs11053646
OLR1
0.010 GeneticVariation BEFREE No significant difference was observed in the genotypic frequencies of OLR1 rs11053646 (P=0.87) or in IL17A rs8193037 and rs3819025 (P=0.80 and 0.92, respectively) polymorphisms between patients with FP artery disease and controls. 28450958

2017
dbSNP: rs3819025
rs3819025
IL17A
0.010 GeneticVariation BEFREE No significant difference was observed in the genotypic frequencies of OLR1 rs11053646 (P=0.87) or in IL17A rs8193037 and rs3819025 (P=0.80 and 0.92, respectively) polymorphisms between patients with FP artery disease and controls. 28450958

2017
dbSNP: rs886039303
rs886039303
ACTA2 ; STAMBPL1
0.010 GeneticVariation BEFREE Cerebral arteriopathy associated with heterozygous Arg179Cys mutation in the ACTA2 gene: Report in 2 newborn siblings. 27567161

2017
dbSNP: rs28935490
rs28935490
GLA ; RPL36A-HNRNPH2
0.010 GeneticVariation BEFREE D313Y might broaden the spectrum of hereditary small artery diseases of the brain, which preferably occur in young adults without classical risk factors. 23393592

2013
dbSNP: rs2762939
rs2762939
CYP24A1
0.010 GeneticVariation BEFREE One of the 4 SNPs, rs2762939, was associated with CAC quantity in both the Genetic Epidemiology Network of Arteriopathy (P=0.007) and Penn Coronary Artery Calcification (P=0.01) studies. 20847308

2010
dbSNP: rs10811661
rs10811661 		0.010 GeneticVariation BEFREE The association of rs10811661-T to T2D replicates in our samples, but the variant does not associate with any of the five arterial diseases examined. 18176561

2008
dbSNP: rs1458766475
rs1458766475
SELE ; C1orf112
0.010 GeneticVariation BEFREE Ser128Arg gene polymorphism for E-selectin and severity of atherosclerotic arterial disease. 15179350

2004
dbSNP: rs5361
rs5361
SELE ; C1orf112
0.010 GeneticVariation BEFREE Ser128Arg gene polymorphism for E-selectin and severity of atherosclerotic arterial disease. 15179350

2004