Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2305603
rs2305603
COL14A1
0.010 GeneticVariation BEFREE Although there was no significant association between the COL3A1 SNP and POP, there was a trend toward significance for COL14A1 SNP (rs2305603), COL4A2 SNP (rs74941798), two COL1A1 SNPs (rs2586488 and rs2249492) and three COL18A1 SNPs (rs1050351, rs56335679, and rs55690336), and POP. 31663982

2020
dbSNP: rs74941798
rs74941798
COL4A2
0.010 GeneticVariation BEFREE Although there was no significant association between the COL3A1 SNP and POP, there was a trend toward significance for COL14A1 SNP (rs2305603), COL4A2 SNP (rs74941798), two COL1A1 SNPs (rs2586488 and rs2249492) and three COL18A1 SNPs (rs1050351, rs56335679, and rs55690336), and POP. 31663982

2020
dbSNP: rs2586488
rs2586488
COL1A1
0.010 GeneticVariation BEFREE Although there was no significant association between the COL3A1 SNP and POP, there was a trend toward significance for COL14A1 SNP (rs2305603), COL4A2 SNP (rs74941798), two COL1A1 SNPs (rs2586488 and rs2249492) and three COL18A1 SNPs (rs1050351, rs56335679, and rs55690336), and POP. 31663982

2020
dbSNP: rs2249492
rs2249492
COL1A1
0.010 GeneticVariation BEFREE Although there was no significant association between the COL3A1 SNP and POP, there was a trend toward significance for COL14A1 SNP (rs2305603), COL4A2 SNP (rs74941798), two COL1A1 SNPs (rs2586488 and rs2249492) and three COL18A1 SNPs (rs1050351, rs56335679, and rs55690336), and POP. 31663982

2020
dbSNP: rs55690336
rs55690336
SLC19A1 ; COL18A1
0.010 GeneticVariation BEFREE Although there was no significant association between the COL3A1 SNP and POP, there was a trend toward significance for COL14A1 SNP (rs2305603), COL4A2 SNP (rs74941798), two COL1A1 SNPs (rs2586488 and rs2249492) and three COL18A1 SNPs (rs1050351, rs56335679, and rs55690336), and POP. 31663982

2020
dbSNP: rs56335679
rs56335679
SLC19A1 ; COL18A1
0.010 GeneticVariation BEFREE Although there was no significant association between the COL3A1 SNP and POP, there was a trend toward significance for COL14A1 SNP (rs2305603), COL4A2 SNP (rs74941798), two COL1A1 SNPs (rs2586488 and rs2249492) and three COL18A1 SNPs (rs1050351, rs56335679, and rs55690336), and POP. 31663982

2020
dbSNP: rs2228480
rs2228480
ESR1
0.010 GeneticVariation BEFREE An association with pelvic organ prolapse was seen in individual studies for estrogen receptor alpha (ER-α) rs2228480 GA, COL3A1 exon 31, chromosome 9q21 (heterogeneity logarithm of the odds score 3.41) as well as 6 single nucleotide polymorphisms identified by a genome-wide association study. 24721264

2014
dbSNP: rs17847075
rs17847075
ESR1
0.010 GeneticVariation BEFREE ESR1 rs17847075 genotype AG in the dominant model (P = 0.008) or heterozygous model (P = 0.045), ESR1 rs2234693 genotype TC in the dominant model (P = 0.008) or heterozygous model (P = 0.028), and ZFAT rs1036819 genotype CC and allele C in the recessive model (P = 0.042) were significantly associated with POP risk in Xinjiang woman. 31270553

2020
dbSNP: rs2234693
rs2234693
ESR1
0.010 GeneticVariation BEFREE ESR1 rs17847075 genotype AG in the dominant model (P = 0.008) or heterozygous model (P = 0.045), ESR1 rs2234693 genotype TC in the dominant model (P = 0.008) or heterozygous model (P = 0.028), and ZFAT rs1036819 genotype CC and allele C in the recessive model (P = 0.042) were significantly associated with POP risk in Xinjiang woman. 31270553

2020
dbSNP: rs1036819
rs1036819
ZFAT ; ZFAT-AS1
0.720 GeneticVariation BEFREE ESR1 rs17847075 genotype AG in the dominant model (P = 0.008) or heterozygous model (P = 0.045), ESR1 rs2234693 genotype TC in the dominant model (P = 0.008) or heterozygous model (P = 0.028), and ZFAT rs1036819 genotype CC and allele C in the recessive model (P = 0.042) were significantly associated with POP risk in Xinjiang woman. 31270553

2020
dbSNP: rs10110287
rs10110287
LOC107986922
T 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs10160713
rs10160713 		A 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs11243354
rs11243354
DPP6
C 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs113872281
rs113872281
GUCA1C
G 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs139563135
rs139563135
FHAD1
A 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs144039930
rs144039930
CRYM ; ANKS4B
C 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs201058683
rs201058683 		AT 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs2209875
rs2209875 		G 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs3850352
rs3850352
MIR217HG ; LOC105374690
T 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs58823963
rs58823963
PTPRD
A 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs7035589
rs7035589
CT70
T 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs7187140
rs7187140
LOC107984869
C 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs73318770
rs73318770
STAU2
G 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs740494
rs740494 		G 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015
dbSNP: rs9772809
rs9772809 		T 0.700 GeneticVariation GWASCAT Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative. 26545240

2015