Source: INFERRED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3814113
rs3814113 		A 0.820 GeneticVariation GWASCAT Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. 23544013

2013
dbSNP: rs3814113
rs3814113 		0.820 GeneticVariation GWASCAT GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 23535730

2013
dbSNP: rs3814113
rs3814113 		A 0.820 GeneticVariation GWASDB Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. 23544013

2013
dbSNP: rs3814113
rs3814113 		T 0.820 GeneticVariation GWASCAT The most significant SNP (rs3814113; P = 2.5 x 10(-17)) was genotyped in a further 2,670 ovarian cancer cases and 4,668 controls, confirming its association (combined data odds ratio (OR) = 0.82, 95% confidence interval (CI) 0.79-0.86, P(trend) = 5.1 x 10(-19)). 19648919

2009
dbSNP: rs4691139
rs4691139 		G 0.800 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442

2017
dbSNP: rs17631303
rs17631303
PLEKHM1
G 0.800 GeneticVariation GWASCAT In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4 × 10(-8), HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4 × 10(-8), HR = 1.20, 95% CI: 1.17-1.38). 23544013

2013
dbSNP: rs17631303
rs17631303
PLEKHM1
G 0.800 GeneticVariation GWASDB In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4 × 10(-8), HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4 × 10(-8), HR = 1.20, 95% CI: 1.17-1.38). 23544013

2013
dbSNP: rs183211
rs183211
NSF ; LRRC37A2
A 0.800 GeneticVariation GWASDB Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. 23544013

2013
dbSNP: rs183211
rs183211
NSF ; LRRC37A2
A 0.800 GeneticVariation GWASCAT Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. 23544013

2013
dbSNP: rs4691139
rs4691139 		G 0.800 GeneticVariation GWASCAT In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4 × 10(-8), HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4 × 10(-8), HR = 1.20, 95% CI: 1.17-1.38). 23544013

2013
dbSNP: rs4691139
rs4691139 		G 0.800 GeneticVariation GWASDB In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4 × 10(-8), HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4 × 10(-8), HR = 1.20, 95% CI: 1.17-1.38). 23544013

2013
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. 22608338

2012
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR Epidermal growth factor receptor blockers for the treatment of ovarian cancer. 21975775

2011
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. 21683865

2011
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR Improved survival with vemurafenib in melanoma with BRAF V600E mutation. 21639808

2011
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR Inhibition of mutated, activated BRAF in metastatic melanoma. 20818844

2010
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer. 19018267

2008
dbSNP: rs113488022
rs113488022
BRAF
T 0.750 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002
dbSNP: rs28897672
rs28897672
BRCA1
C 0.730 CausalMutation CLINVAR

dbSNP: rs11571833
rs11571833
BRCA2
T 0.720 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016
dbSNP: rs2072590
rs2072590
HAGLR ; HAGLROS
0.720 GeneticVariation GWASCAT GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. 23535730

2013
dbSNP: rs2072590
rs2072590
HAGLR ; HAGLROS
T 0.720 GeneticVariation GWASCAT A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. 20852632

2010
dbSNP: rs10069690
rs10069690
TERT
T 0.710 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442

2017
dbSNP: rs11651755
rs11651755
HNF1B
C 0.710 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442

2017
dbSNP: rs8037137
rs8037137
RCCD1
C 0.710 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442

2017