|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MTHFR C677T genetic polymorphism in combination with serum vitamin B<sub>2</sub>, B<sub>12</sub> and aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and esophageal precancerous lesions: a case-control study.
|
31754346 |
2019 |
|
rs12435483
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significantly decreased risk of cervical precancerous lesions for the TC genotype of rs12435483 in the <i>TRAF3</i> gene (OR<sub>adjusted</sub> = 0.67, 95% CI, 0.45-0.98) was also found.
|
30463990 |
2019 |
|
rs6052130
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, <i>MAVS</i> rs6052130-mutant individuals have an increased vulnerability to high-risk HPV-induced cervical precancerous lesions.
|
30463990 |
2019 |
|
rs78303930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present study comparatively analyzed serial autopsies of Japanese patients (n=2,206; males, 1,225; females, 981; median, 80.7 years old; range, 33-104 years old) with malignant tumors of whole organs, with respect to the clinical information, and 5 single nucleotide polymorphisms of the nestin gene. p.A1199P associated with pancreatic cancer (odds ratio, 4.4; 95% confidence interval, 1.9-10.0, P=0.001) while it did not associate with malignant neoplasms in other organs. p.A1199P did not associate with precancerous lesions of the pancreas.
|
30988821 |
2019 |
|
rs879253942
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MTHFR C677T genetic polymorphism in combination with serum vitamin B<sub>2</sub>, B<sub>12</sub> and aberrant DNA methylation of P16 and P53 genes in esophageal squamous cell carcinoma and esophageal precancerous lesions: a case-control study.
|
31754346 |
2019 |
|
rs14035
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five single nucleotide polymorphisms (SNPs), including Ran-GTP (<i>RAN</i>) rs14035, exportin-5 (<i>XPO5</i>) rs11077, <i>DICER1</i> rs3742330, <i>DICER1</i> rs13078, and <i>TARBP2</i> rs784567, were genotyped in a case-control study to estimate risk factors of cervical precancerous lesions.
|
29853562 |
2018 |
|
rs1966265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our study demonstrated that FGFR4 rs2011077 and rs1966265 are associated with the progression of cervical normal tissues to precancerous lesions in Taiwanese women.
|
28378614 |
2018 |
|
rs2011077
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our study demonstrated that FGFR4 rs2011077 and rs1966265 are associated with the progression of cervical normal tissues to precancerous lesions in Taiwanese women.
|
28378614 |
2018 |
|
rs3742330
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A two-factor (<i>DICER1</i> rs3742330 and human papillomavirus (HPV) infection) and two three-factor (model 1: rs3742330, passive smoking, and HPV infection; model 2: rs3742330, abortion history, and HPV infection) interaction models for cervical precancerous lesions were identified.
|
29853562 |
2018 |
|
rs7708357
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Real-time polymerase chain reaction and genotyping were used to detect the genotype frequencies of 4 FGFR4 single-nucleotide polymorphisms (SNPs), rs351855 (C/T, Gly388Arg), rs2011077 (G/A), rs7708357 (G/A), and rs1966265 (Ile10Val), in 138 patients with invasive cancer, 89 with precancerous lesions of uterine cervix, and 335 normal controls.
|
28378614 |
2018 |
|
rs784567
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five single nucleotide polymorphisms (SNPs), including Ran-GTP (<i>RAN</i>) rs14035, exportin-5 (<i>XPO5</i>) rs11077, <i>DICER1</i> rs3742330, <i>DICER1</i> rs13078, and <i>TARBP2</i> rs784567, were genotyped in a case-control study to estimate risk factors of cervical precancerous lesions.
|
29853562 |
2018 |
|
rs16970849
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to evaluate the association of two SNPs of EVER1/2 genes' region (rs2290907, rs16970849) and the FAS-670 polymorphism with the susceptibility to precancerous lesions and cervical cancer in a Greek population.
|
27899077 |
2016 |
|
rs2290907
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of the study was to evaluate the association of two SNPs of EVER1/2 genes' region (rs2290907, rs16970849) and the FAS-670 polymorphism with the susceptibility to precancerous lesions and cervical cancer in a Greek population.
|
27899077 |
2016 |
|
rs281432
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Compared to homozygous wild CC, heterozygous CG, homozygous mutant GG, or genotypes with CG/GG display increased risks or a tendency of precancerous lesions or invasive cancer with strong power in rs281432.
|
26377999 |
2016 |
|
rs3093030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The homozygotic mutant alleles TT in rs3093030 and homozygotic mutant alleles GG in rs5498 were associated with a higher risk of invasive cancer and precancerous lesions, respectively, but with lower power.
|
26377999 |
2016 |
|
rs311678
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our results indicate that the rs311678 polymorphism in the cGAS gene confers genetic susceptibility to cervical precancerous lesions.
|
27705945 |
2016 |
|
rs5498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The homozygotic mutant alleles TT in rs3093030 and homozygotic mutant alleles GG in rs5498 were associated with a higher risk of invasive cancer and precancerous lesions, respectively, but with lower power.
|
26377999 |
2016 |
|
rs10759932
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TLR4 rs10759932 TC and C carriers were associated with a lower risk in developing precancerous lesions in the stomach in a Chinese Han population.
|
24269697 |
2014 |
|
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed that frequencies of TLR-4 Asp299Gly variants were comparable between patients and control subjects, and also between positive and negative groups of precancerous lesions in patients.
|
18082569 |
2007 |