| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.720 | GeneticVariation | BEFREE | The genotype of rs10744777 (CT/TT) was associated with risk of ischemic stroke in males (OR = 1.99, 95% CI = 1.15-3.42, P = 0.013). | 30077765 | 2018 |
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|
T | 0.720 | GeneticVariation | GWASCAT | Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. | 26708676 | 2016 |
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|
0.720 | GeneticVariation | BEFREE | In an overall analysis of 17,970 cases of ischemic stroke and 70,764 controls, we identified a novel association on chromosome 12q24 (rs10744777, odds ratio [OR] 1.10 [1.07-1.13], p = 7.12 × 10(-11)) with ischemic stroke. | 25031287 | 2014 |
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|
0.020 | GeneticVariation | BEFREE | <b>Conclusion:</b> Our meta-analysis indicates that the <i>ALDH2</i> rs671 G>A polymorphism may play an important role in the occurrence of IS by reducing the activity of ALDH2 and interfering with the metabolic processes involving acetaldehyde. | 31114208 | 2019 |
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|
0.020 | GeneticVariation | BEFREE | Aldehyde dehydrogenase 2 rs671G>A polymorphism and ischemic stroke risk in Chinese population: a meta-analysis. | 31114208 | 2019 |
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|
0.020 | GeneticVariation | BEFREE | After three months follow-up, we found a poorer functional outcome of ischemic stroke associated with the rs886205 GA genotype (OR = 1.76, 95% CI 1.03-3.00, P = 0.057) in males. | 30077765 | 2018 |
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|
0.020 | GeneticVariation | BEFREE | In addition, we established that the "AA" genotype (OR = 5.99; 95% CI = 1.11-32.23; <i>p</i> = 0.037) for rs886205 and the "AA" genotype (OR = 8.93; 95% CI = 1.31-60.78; <i>p</i> = 0.025) for rs7296651 were associated with increased ischemic stroke risk. | 29254215 | 2017 |
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|
0.020 | GeneticVariation | BEFREE | There was a significant difference in the distribution of the allele and genotype frequencies of the rs671 polymorphism between PSE patients and ischemic stroke (IS) patients. | 25313998 | 2014 |
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|
0.010 | GeneticVariation | BEFREE | In addition, we established that the "AA" genotype (OR = 5.99; 95% CI = 1.11-32.23; <i>p</i> = 0.037) for rs886205 and the "AA" genotype (OR = 8.93; 95% CI = 1.31-60.78; <i>p</i> = 0.025) for rs7296651 were associated with increased ischemic stroke risk. | 29254215 | 2017 |