DisGeNET - a database of gene-disease associations

Ischemic stroke, C0948008

Gene: ZFHX3 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs7193343

ZFHX3

0.710

GeneticVariation

GWASCAT

Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study.

26708676

2016

dbSNP:

rs7193343

ZFHX3

0.710

GeneticVariation

BEFREE

Nonparametric linkage analysis revealed that the rs1800796 polymorphism in the interleukin-6 (IL-6) gene is significantly linked to the small arterial occlusion (SAO) subtype (p=0.022), while the rs7193343 polymorphism in the ZFHX3 gene is linked to IS (p=0.002) under the dominant model.

25325233

2014

dbSNP:

rs879324

ZFHX3

0.010

GeneticVariation

BEFREE

There was no association between clinical severity and recurrence with variants rs2383207 (CDKN2B-AS1) for atherothrombotic IS and variants rs879324 (ZFHX3), rs966221 (PDE4D), and rs152312 (PDE4D) for cardioembolic IS.

31757599

2020