|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The current investigation provided verification that h</span>sa-mir-499 rs3746444 A/G polymorphism may be associated with a significantly increased risk of IS in an Iranian population.
|
30229913 |
2019 |
|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
In particular, the associations of rs2910164 (miRNA-146A), rs11614913 (miRNA-196A2), and rs3746444 (miRNA-499A) were intensively studied in IS.
|
31781304 |
2019 |
|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
These results indicate that the GG genotype of miR-146a (rs2910164) and CC genotype of miR-149 (rs2292832) may confer increased susceptibility to IS, while miR-196a2 (rs11614913) and miR-499 (rs3746444) polymorphisms may not be associated with IS risk in Asian populations.
|
30254431 |
2018 |
|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> MiR-499 A>G (rs3746444) G allele and AG, AG + AA genotype might be risk factors of IS in Chinese.
|
29643803 |
2018 |
|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The genetic polymorphism of <i>miR-499A>G</i> (rs3746444) was related to ischemic stroke, and G allele and AG genotype may increase the risk of ischemic stroke in the population of Guangxi in China.
|
29113388 |
2017 |
|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Using the TaqMan assay, we evaluated the association of hsa-miR-146a/rs2910164, hsa-miR-196a2/rs11614913, and hsa-miR-499/rs3746444 polymorphisms with the risk of ischemic stroke in a Chinese population with 531 ischemic stroke patients and 531 control subjects.
|
25658319 |
2015 |
|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Rs11614913 T allele might be associated with higher IS risk under the dominant model (OR=1.45, 95% CI=1.19-1.78, p=0.0003), while rs3746444 A allele might be associated with decreased IS risk under the homozygous model (OR=0.48, 95% CI=0.23-0.98, p=0.04) only in Chinese, but not in Koreans.
|
26608782 |
2015 |
|
rs3746444
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The present study provided evidence that hsa-mir-499/rs3746444 A/G polymorphism might be associated with a significantly increased risk of ischemic stroke in a Chinese population, indicating that the common genetic polymorphism in pre-microRNAs contributed to the pathogenesis of ischemic stroke.
|
24178064 |
2014 |