|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated cross-sectionally in 1,435 individuals with lifetime MDD the impact of childhood abuse (CA) and recent life events on serum BDNF levels and assessed whether the impact of these events was moderated by the BDNF Val(66)Met polymorphism.
|
20703451 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We investigated the relationship between a brain-derived neurotrophic factor (BDNF) polymorphism (Val66Met) and the clinical response of patients with major depressive disorder to selective serotonin reuptake inhibitors (SSRIs; here, paroxetine and sertraline).
|
21338649 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Both clinical and pharmacological studies have implicated the common single nucleotide polymorphism (SNP) at position 196, Val66Met in the pathophysiology of major depressive disorder (MDD), and antidepressant response.
|
21188787 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Moreover, there was no significant difference in normalized HCV between 5HTTLPR diallelic and triallelic classifications or between the BDNF Val66Met</span> genotypes in MDD patients, although there was a relationship between BDNF Val66Met and ICV.
|
21692988 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Although not observed in younger adult cohorts, in older individuals the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with major depressive disorder (MDD) risk.
|
20195291 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The BDNF val66met polymorphism may play a salient role in structural alterations of the hippocampus in older adults with MDD.
|
21218562 |
2011 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Meta-analysis of BDNF Val66Met polymorphism association with treatment response in patients with major depressive disorder.
|
20167454 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To determine the effect of BDNF gene val66met polymorphism on serum BDNF levels in drug-free patients with major depressive disorder (MDD) and healthy subjects, that differ by gender.
|
19589373 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results do not support the hypothesis that the Val66Met promoter polymorphism in the BDNF gene influences the therapeutic response to mirtazapine in Korean MDD patients.
|
19493959 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results suggest that the BDNF Val66Met polymorphism is of greater importance in the development of MDD in men than in women.
|
18852698 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Brain derived neurotrophic factor gene polymorphism (Val66Met) and short-term antidepressant response in major depressive disorder.
|
20674983 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results indicate that there was a lack of association between severity of depression and BDNF Val66Met polymorphism in Chinese patients with MDD.
|
20016225 |
2010 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To conclude, we did not replicate the Val66Met effect on hippocampal volume in neither patients with major depression nor in healthy participants.
|
19668114 |
2009 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A functional polymorphism of the brain-derived neurotrophic factor, BDNF Val66Met, is associated with risk for major depression alongside impairments in memory and selective attention.
|
18721847 |
2008 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
To examine the effect of the BDNF Val66Met polymorphism on hippocampal and amygdala volumes in patients with major depression and in healthy control subjects.
|
17404118 |
2007 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that the BDNF Val66Met polymorphism is not related to the development of MDD but related to clinical features of MDD in a Japanese population.
|
17510948 |
2007 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Several studies have linked 5-HT1A C1019G and BDNF G196A (Val66Met) gene polymorphisms to major depressive disorder (MDD) and the actions of antidepressants.
|
17401528 |
2007 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Brain-derived neurotrophic factor (BDNF) polymorphisms G196A and C270T are not associated with response to electroconvulsive therapy in major depressive disorder.
|
17036259 |
2007 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder.
|
16979146 |
2006 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We genotyped the BDNF-gene Val66Met polymorphism in 110 elderly inpatients diagnosed with major depression and 171 age- and sex-similar control subjects.
|
16343697 |
2006 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The present study tested the hypothesis that the BDNF-gene Val66Met polymorphism is associated with MDD, its clinical manifestations, and antidepressant response.
|
14582140 |
2003 |