|
rs4570625
|
|
|
0.030 |
GeneticVariation |
BEFREE |
They aimed to investigate the alterations in the cortical gyrification of the prefrontal cortex and anterior cingulate cortex and their association with the TPH2 rs4570625 polymorphism in patients with MDD.
|
27807918 |
2017 |
|
rs120074175
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Chinese Han individuals with at least one rs11178997 T allele or rs120074175 A allele are susceptible to MD even in the relative absence of high-negative life events.
|
26386440 |
2015 |
|
rs4570625
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Individuals carrying the T(-) genotype of rs4570625 (GG), T(-) genotype of rs11178997 (AA), or A(-) genotype of rs120074175 (GG) were susceptible to MD only when exposed to high-negative life events.
|
26386440 |
2015 |
|
rs4570625
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The synthesis of the data shown that two SNPs (rs4570625 and rs17110747) were associated with MDD using fixed effects models.
|
22693556 |
2012 |
|
rs120074175
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This mutant is equivalent to a rare human variant (R441H) identified in few individuals with unipolar major depression.
|
18212115 |
2008 |
|
rs120074175
|
|
|
0.030 |
GeneticVariation |
BEFREE |
It was recently reported that a rare functional variant, R441H, in the human tryptophan hydroxylase-2 gene (hTPH2) could represent an important risk factor for unipolar major depression (UP) since it was originally found in 10% of UP patients (vs. 1.4% in control subjects).
|
16581035 |
2006 |
|
rs4290270
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Hence, rs4290270 could potentially serve as a reliable biomarker to identify MDD patients with early wakening symptom.
|
30519155 |
2018 |
|
rs4290270
|
|
|
0.020 |
GeneticVariation |
BEFREE |
TPH2 rs4290270 was genotyped in 165 suicide attempters and 188 suicide non-attempters diagnosed with major depressive disorder, bipolar disorder and schizophrenia.
|
28084537 |
2017 |
|
rs17110747
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The synthesis of the data shown that two SNPs (rs4570625 and rs17110747) were associated with MDD using fixed effects models.
|
22693556 |
2012 |
|
rs17110747
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In single-marker-based analysis, the rs17110747-G homozygote polymorphism was found to be more frequent in the MDD patients than in the controls (P=0.002).
|
19272410 |
2009 |
|
rs11178997
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Chinese Han individuals with at least one rs11178997 T allele or rs120074175 A allele are susceptible to MD even in the relative absence of high-negative life events.
|
26386440 |
2015 |
|
rs7305115
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Effect of tryptophan hydroxylase-2 rs7305115 SNP on suicide attempts risk in major depression.
|
20738857 |
2010 |