Gene: CNR1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1049353
rs1049353
CNR1
0.040 GeneticVariation BEFREE Haplotype frequency distributions between MD sample and controls showed a significant difference for Block 1 (rs806368-rs1049353-rs806371) (p = 0.008). 23407780

2013
dbSNP: rs1049353
rs1049353
CNR1
0.040 GeneticVariation BEFREE The rs1049353 polymorphism also buffered the effects of childhood physical abuse on major depressive disorder; however, this influence was largely attributable to anhedonic depression. 22393204

2012
dbSNP: rs1049353
rs1049353
CNR1
0.040 GeneticVariation BEFREE We assessed the CB1 receptor gene (CNR1) single nucleotide polymorphism (SNP) rs1049353 (1359 G/A) and the fatty acid amide hydrolase (FAAH) gene rs324420 SNP (cDNA 385C to A) for their associations with MD and/or BD in 83 Caucasian patients with recurrent MD, 134 Caucasian individuals with BD, and 117 Caucasian healthy subjects. 20080186

2010
dbSNP: rs1049353
rs1049353
CNR1
0.040 GeneticVariation BEFREE Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression. 18579347

2008
dbSNP: rs2023239
rs2023239
CNR1
0.010 GeneticVariation BEFREE The minor C allele of rs2023239 showed an independent protective effect against lifetime MDD after adjustment for potential confounders. 26331953

2015
dbSNP: rs1535255
rs1535255
CNR1
0.010 GeneticVariation BEFREE The role of CNR1 gene (rs806368, rs1049353, rs806371, rs806377 and rs1535255) was investigated in 319 outpatients with MD and 150 healthy individuals. 23407780

2013
dbSNP: rs806368
rs806368
CNR1
0.010 GeneticVariation BEFREE Haplotype frequency distributions between MD sample and controls showed a significant difference for Block 1 (rs806368-rs1049353-rs806371) (p = 0.008). 23407780

2013
dbSNP: rs806371
rs806371
CNR1
0.010 GeneticVariation BEFREE Haplotype frequency distributions between MD sample and controls showed a significant difference for Block 1 (rs806368-rs1049353-rs806371) (p = 0.008). 23407780

2013
dbSNP: rs12720071
rs12720071
CNR1
0.010 GeneticVariation BEFREE Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression. 18579347

2008