|
rs4718789
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study.
|
28447399 |
2017 |
|
rs4978818
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association study of HIV-associated neurocognitive disorder (HAND): A CHARTER group study.
|
28447399 |
2017 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment.
|
31771052 |
2020 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers.
|
30775992 |
2019 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
To compare the results of neuropsychological tests, evoked potentials N200 and P300 and polymorphisms of ApoE and BDNF rs6265 between patients with normal cognition and those with mild cognitive impairment (MCI) and Alzheimer's dementia (AD).
|
28833437 |
2018 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Physical exercise improves peripheral BDNF levels and cognitive functions in mild cognitive impairment elderly with different bdnf Val66Met genotypes.
|
25062900 |
2015 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Association between BDNF polymorphism (Val66Met) and executive function in patients with amnestic mild cognitive impairment or mild Alzheimer disease.
|
22699449 |
2012 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Although Val66Met polymorphisms were not associated with the cross-sectional diagnoses of MCI or AD, the presence of Met-BDNF allele was associated with a higher risk of disease-progression in patients with MCI (OR=3.0 CI(95%) [1.2-7.8], P=0.02).
|
20491609 |
2010 |
|
rs6265
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The BDNF Val66Met polymorphism was not associated with serum BDNF or cognitive function in aMCI patients.
|
18505307 |
2008 |
|
rs759834365
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment.
|
31771052 |
2020 |
|
rs759834365
|
|
|
0.060 |
GeneticVariation |
BEFREE |
A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers.
|
30775992 |
2019 |
|
rs759834365
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Physical exercise improves peripheral BDNF levels and cognitive functions in mild cognitive impairment elderly with different bdnf Val66Met genotypes.
|
25062900 |
2015 |
|
rs759834365
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Association between BDNF polymorphism (Val66Met) and executive function in patients with amnestic mild cognitive impairment or mild Alzheimer disease.
|
22699449 |
2012 |
|
rs759834365
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Although Val66Met polymorphisms were not associated with the cross-sectional diagnoses of MCI or AD, the presence of Met-BDNF allele was associated with a higher risk of disease-progression in patients with MCI (OR=3.0 CI(95%) [1.2-7.8], P=0.02).
|
20491609 |
2010 |
|
rs759834365
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The BDNF Val66Met polymorphism was not associated with serum BDNF or cognitive function in aMCI patients.
|
18505307 |
2008 |
|
rs11136000
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Contrary to other studies on Asian populations, this study demonstrated an association between rs11136000 and MCI in an elderly Iranian population.
|
30560405 |
2019 |
|
rs11136000
|
|
|
0.040 |
GeneticVariation |
BEFREE |
To evaluate cognitive performance and presence of polymorphisms of the genes SORL1(rs11218304), PVRL2(rs6859), CR1(rs6656401), TOMM40(rs2075650), APOE (isoforms ɛ2, ɛ3, ɛ4), PICALM(rs3851179), GWAS_14q(rs11622883), BIN1(rs744373), and CLU (rs227959 and rs11136000) in patients with MCI and healthy individuals.
|
30503753 |
2018 |
|
rs11136000
|
|
|
0.040 |
GeneticVariation |
BEFREE |
CLU-rs11136000-G associated with worse baseline memory and incident MCI/LOAD.
|
25189118 |
2015 |
|
rs11136000
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Plasma clusterin levels and the rs11136000 genotype in individuals with mild cognitive impairment and Alzheimer's disease.
|
24117116 |
2013 |
|
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
These results confirm the importance of the COMTp.Val158Met genotype on tasks assessing attention and cognitive flexibility in midlife but not in healthy aging and the development of MCI.
|
26489081 |
2016 |
|
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Influence of COMT Val158Met polymorphism on Alzheimer's disease and mild cognitive impairment in Italian patients.
|
22890094 |
2012 |
|
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The COMT Val158 Met polymorphism as an associated risk factor for Alzheimer disease and mild cognitive impairment in APOE 4 carriers.
|
19793392 |
2009 |
|
rs1416580204
|
|
|
0.020 |
GeneticVariation |
BEFREE |
G82S polymorphism of receptor for advanced glycation end products gene and serum soluble RAGE levels in mild cognitive impairment and dementia of Alzheimer's type patients in Turkish population.
|
30389362 |
2019 |
|
rs2070600
|
|
|
0.020 |
GeneticVariation |
BEFREE |
G82S polymorphism of receptor for advanced glycation end products gene and serum soluble RAGE levels in mild cognitive impairment and dementia of Alzheimer's type patients in Turkish population.
|
30389362 |
2019 |
|
rs363050
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Moreover, distribution of the STX1a rs4717806 allele in SNAP-25 rs363050 AA carriers was significantly different between MCI and HC (p = 0.018).
|
30958380 |
2019 |