|
rs231775
|
|
|
0.050 |
GeneticVariation |
BEFREE |
rs231775, rs4553808 and rs5742909 may be used as predictive genetic biomarkers for cancer predisposition.
|
29794444 |
2018 |
|
rs231775
|
|
|
0.050 |
GeneticVariation |
BEFREE |
No significant associations with PFS were found.<b>Conclusions:</b> The G-allele of rs231775 in the <i>CTLA-4</i> gene is associated with an improved OS in sunitinib-treated cc-mRCC patients and could potentially be used as a prognostic biomarker.<i>Clin Cancer Res; 24(10); 2350-6.©2018 AACR</i>.
|
29490989 |
2018 |
|
rs231775
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our data show that the CTLA4 genotype rs231775 AA may be one of risk factors for the development of malignancy and haplotype TACAG was susceptible haplotype in Chinese kidney transplant recipients.
|
25667935 |
2015 |
|
rs231775
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Taken together, the results suggest that CTLA4 rs231775 may serve as a common cancer susceptibility marker.
|
20538028 |
2010 |
|
rs231775
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Interestingly, we have recently shown that an SNP in the CTLA-4 coding region (49A > G) is also associated with susceptibility to human cancer, but the risk allele for susceptibility to cancer (allele A) is the opposite of that found for susceptibility to autoimmune disease (allele G), which has been confirmed by a meta-analysis of reported studies.
|
19638588 |
2009 |
|
rs733618
|
|
|
0.030 |
GeneticVariation |
BEFREE |
rs231775, rs4553808 and rs5742909 but not rs3087243 and rs733618 were significantly related to cancer risk.
|
29794444 |
2018 |
|
rs733618
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We investigated the association of five CTLA4 single-nucleotide polymorphisms (SNPs) (rs733618 C/T, rs4553808 A/G, rs5742909 C/T, rs231775 A/G, and rs3087243 G/A) with de novo malignancy in 1463 Chinese renal transplantation (RT) recipients who underwent a 192-month follow-up.
|
25667935 |
2015 |
|
rs733618
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Lack of association between cytotoxic T-lymphocyte antigen 4 (CTLA-4) -1722T/C (rs733618) polymorphism and cancer risk: from a case-control study to a meta-analysis.
|
24710335 |
2014 |
|
rs3087243
|
|
|
0.020 |
GeneticVariation |
BEFREE |
rs231775, rs4553808 and rs5742909 but not rs3087243 and rs733618 were significantly related to cancer risk.
|
29794444 |
2018 |
|
rs4553808
|
|
|
0.020 |
GeneticVariation |
BEFREE |
rs231775, rs4553808 and rs5742909 may be used as predictive genetic biomarkers for cancer predisposition.
|
29794444 |
2018 |
|
rs5742909
|
|
|
0.020 |
GeneticVariation |
BEFREE |
rs231775, rs4553808 and rs5742909 may be used as predictive genetic biomarkers for cancer predisposition.
|
29794444 |
2018 |
|
rs3087243
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We investigated the association of five CTLA4 single-nucleotide polymorphisms (SNPs) (rs733618 C/T, rs4553808 A/G, rs5742909 C/T, rs231775 A/G, and rs3087243 G/A) with de novo malignancy in 1463 Chinese renal transplantation (RT) recipients who underwent a 192-month follow-up.
|
25667935 |
2015 |
|
rs4553808
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We investigated the association of five CTLA4 single-nucleotide polymorphisms (SNPs) (rs733618 C/T, rs4553808 A/G, rs5742909 C/T, rs231775 A/G, and rs3087243 G/A) with de novo malignancy in 1463 Chinese renal transplantation (RT) recipients who underwent a 192-month follow-up.
|
25667935 |
2015 |
|
rs5742909
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We investigated the association of five CTLA4 single-nucleotide polymorphisms (SNPs) (rs733618 C/T, rs4553808 A/G, rs5742909 C/T, rs231775 A/G, and rs3087243 G/A) with de novo malignancy in 1463 Chinese renal transplantation (RT) recipients who underwent a 192-month follow-up.
|
25667935 |
2015 |
|
rs886041906
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our meta-analysis suggests that the CTLA-4 -1661A/G polymorphism is a potential factor for the susceptibility of cancer, especially in gastric cancer, breast cancer and other cancers, and the CTLA-4 60G/A polymorphism is significantly associated with increased skin cancer risk.
|
24376736 |
2013 |