Gene: CYP2E1 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2031920
rs2031920
CYP2E1 ; LOC107984284
0.030 GeneticVariation BEFREE Our findings indicate that CYP2E1 rs2031920 and COMT rs4680 are not major contributors to lung cancer risk in our Japanese population. 27644662

2016
dbSNP: rs2031920
rs2031920
CYP2E1 ; LOC107984284
0.030 GeneticVariation BEFREE The previous, published data on the association between CYP2E1 RsaI (rs2031920), DraI (rs6413432) polymorphisms and lung cancer risk remained controversial. 25336053

2015
dbSNP: rs2031920
rs2031920
CYP2E1 ; LOC107984284
0.030 GeneticVariation BEFREE In haplotype analysis, haplotype G-C-C-T (in order of rs689466, rs5275, rs2031920 and rs6413432) decreased the odds of lung cancer by 28% (95% CI: 0.51-0.93; P = 0.019) after adjusting for confounding factors, whereas haplotype A-T-T-T had 1.49-fold (95% CI: 1.21-1.79; P = 0.012) increased risk for lung cancer. 22761909

2012
dbSNP: rs6413432
rs6413432
CYP2E1
0.020 GeneticVariation BEFREE The previous, published data on the association between CYP2E1 RsaI (rs2031920), DraI (rs6413432) polymorphisms and lung cancer risk remained controversial. 25336053

2015
dbSNP: rs6413432
rs6413432
CYP2E1
0.020 GeneticVariation BEFREE In haplotype analysis, haplotype G-C-C-T (in order of rs689466, rs5275, rs2031920 and rs6413432) decreased the odds of lung cancer by 28% (95% CI: 0.51-0.93; P = 0.019) after adjusting for confounding factors, whereas haplotype A-T-T-T had 1.49-fold (95% CI: 1.21-1.79; P = 0.012) increased risk for lung cancer. 22761909

2012
dbSNP: rs3813867
rs3813867
CYP2E1 ; LOC107984284
0.010 GeneticVariation BEFREE Many studies have examined the association between the CYP2E1 Rsa Ι/Pst Ι (rs3813867) polymorphism gene polymorphisms and lung cancer risk in various populations, but their results have been inconsistent. 25945422

2015
dbSNP: rs1467974326
rs1467974326
CYP2E1 ; LOC107984284
0.010 GeneticVariation BEFREE However, only four of the previously reported associations with polymorphisms in the GSTP1 (Ala14Val), SOD2 (Val16Ala), EPHX1 (His139Arg) genes and the NAT1 fast acetylator phenotype remained significantly associated with lung cancer. 18258609

2008
dbSNP: rs563043306
rs563043306
CYP2E1 ; LOC107984284
0.010 GeneticVariation BEFREE However, only four of the previously reported associations with polymorphisms in the GSTP1 (Ala14Val), SOD2 (Val16Ala), EPHX1 (His139Arg) genes and the NAT1 fast acetylator phenotype remained significantly associated with lung cancer. 18258609

2008