|
rs7765004
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association Study of Event-Free Survival in Diffuse Large B-Cell Lymphoma Treated With Immunochemotherapy.
|
26460308 |
2015 |
|
rs10484561
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, in a follow-up analysis of the top 6 FL-associated SNPs in 4,449 cases of other NHL subtypes, rs10484561 was associated with risk of diffuse large B-cell lymphoma (OR(combined) = 1.36, P(combined) = 1.4 × 10(-7)).
|
21533074 |
2011 |
|
rs1390458638
|
|
|
0.010 |
GeneticVariation |
BEFREE |
B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice.
|
27048211 |
2016 |
|
rs2231142
|
|
|
0.010 |
GeneticVariation |
BEFREE |
ABCG2 Q141K polymorphism is associated with chemotherapy-induced diarrhea in patients with diffuse large B-cell lymphoma who received frontline rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone chemotherapy.
|
19032367 |
2008 |
|
rs1880030
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variants in BCL7A were strongly related to diffuse large B-cell lymphoma only, particularly rs1880030 (OR(AG), 1.34; 95% CI, 1.08-1.68; OR(AA), 1.60; 95% CI, 1.22-2.08; P(trend) = 0.0004).
|
19336552 |
2009 |
|
rs113488022
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H).
|
22575864 |
2012 |
|
rs121913377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H).
|
22575864 |
2012 |
|
rs6449182
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Given the importance of understanding the genetic variations involved in the pathogenesis of non-Hodgkin's lymphoma (NHL), this pilot study was designed to investigate the impact of CD38 (184C/G; rs6449182) and IL-6 (-174 G/C; rs1800795) gene polymorphism on susceptibility of Egyptians to diffuse large B cell lymphoma (DLBCL); major types of NHL.
|
25564959 |
2015 |
|
rs20551
|
|
|
0.010 |
GeneticVariation |
BEFREE |
EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP.
|
28725161 |
2017 |
|
rs2234922
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The weak, nonsignificant overall association between benzene and diffuse large B-cell lymphoma (OR = 1.29, 95% CI: 0.84, 1.98) was increased among women AA for rs2234922 in the microsomal epoxide hydrolase gene, EPHX1 (OR = 1.77, 95% CI: 1.06, 2.97; P(interaction) = 0.06).
|
21228414 |
2011 |
|
rs13181
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant interaction with BMI was only observed for WRN (rs1801195; P = 0.004) for T-cell lymphoma and ERCC2 (rs13181; P = 0.002) for diffuse large B-cell lymphoma.
|
23619945 |
2013 |
|
rs1178732315
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lack of a Prognostic Impact of the MyD88 L265P Mutation for Diffuse Large B Cell Lymphoma Patients Undergoing Autologous Stem Cell Transplantation.
|
28847710 |
2017 |
|
rs1227230819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single-base substitution was found in exon 1 (227G>A) of the XBP1 gene in a patient with diffuse large B-cell lymphoma, resulting in a somatic missense mutation (R76K).
|
19380033 |
2009 |
|
rs121913496
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H).
|
22575864 |
2012 |
|
rs28933406
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H).
|
22575864 |
2012 |
|
rs1800890
|
|
|
0.020 |
GeneticVariation |
BEFREE |
IL10 rs1800890 was associated with risk of diffuse large B-cell lymphoma (OR 1.41, CI 1.08-1.85 for minor allele homozygosity) and mantle cell lymphoma (OR 1.77, CI 1.04-3.00).
|
20087644 |
2010 |
|
rs1800890
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The study found that polymorphism in interleukin 10 (IL10; rs1800890) modified the association between occupational exposure to organic solvents and the risk for diffuse large B-cell lymphoma (P(for interaction)=0.0058).
|
22609637 |
2013 |
|
rs1800795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Given the importance of understanding the genetic variations involved in the pathogenesis of non-Hodgkin's lymphoma (NHL), this pilot study was designed to investigate the impact of CD38 (184C/G; rs6449182) and IL-6 (-174 G/C; rs1800795) gene polymorphism on susceptibility of Egyptians to diffuse large B cell lymphoma (DLBCL); major types of NHL.
|
25564959 |
2015 |
|
rs1800797
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, rs1800797 was significantly association with breast cancer, non-Hodgkin's lymphoma, B-cell lymphoma and diffuse large B-cell lymphoma but not gastric cancer.
|
29552316 |
2018 |
|
rs121913238
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H).
|
22575864 |
2012 |
|
rs121913240
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs121913529
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs121913530
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene.
|
9139869 |
1997 |
|
rs17851045
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H).
|
22575864 |
2012 |
|
rs7712513
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genome-Wide Association Study of Event-Free Survival in Diffuse Large B-Cell Lymphoma Treated With Immunochemotherapy.
|
26460308 |
2015 |