Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs895819
rs895819
0.010 GeneticVariation BEFREE Pre-miR-27a rs895819 polymorphism and risk of diffuse large B-cell lymphoma. 31797450

2020

dbSNP: rs12917
rs12917
0.010 GeneticVariation BEFREE After stratification by major NHL histological subtypes, MGMT (rs12917) modified the association between chlorinated solvents and the risk of diffuse large B-cell lymphoma (Pfor interaction=0.0027) and follicular lymphoma (Pfor interaction=0.0024). 22430443

2012

dbSNP: rs2910164
rs2910164
0.010 GeneticVariation BEFREE MicroRNA-146a rs2910164 polymorphism and the risk of diffuse large B cell lymphoma in the Chinese Han population. 25370733

2014

dbSNP: rs2070770
rs2070770
0.010 GeneticVariation BEFREE The significance of single nucleotide polymorphism rs2070770 in CD20 gene in Chinese patients with diffuse large B-cell lymphoma. 24898664

2015

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE Lack of a Prognostic Impact of the MyD88 L265P Mutation for Diffuse Large B Cell Lymphoma Patients Undergoing Autologous Stem Cell Transplantation. 28847710

2017

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P-Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases. 27923841

2017

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE MYD88 expression and L265P mutation in diffuse large B-cell lymphoma. 23380077

2013

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE High frequencies of the hotspot <i>MYD88</i>(L265P) mutation are observed in extranodal diffuse large B-cell lymphoma and Waldenström macroglobulinemia, thereby demonstrating this mutation's potential as a disease marker. 31699794

2019

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice. 27048211

2016

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE Myd-88 L265P constitutive activating mutations are present in at least some cases of the diffuse large B-cell lymphoma form of vitreoretinal lymphoma. 25768255

2015

dbSNP: rs387907272
rs387907272
0.070 GeneticVariation BEFREE Clinicopathologic significance of MYD88 L265P mutation in diffuse large B-cell lymphoma: a meta-analysis. 28496180

2017

dbSNP: rs1057519695
rs1057519695
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs1057519834
rs1057519834
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs11554290
rs11554290
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913237
rs121913237
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913250
rs121913250
0.010 GeneticVariation BEFREE Altogether, one diffuse large B-cell lymphoma and one B-cell chronic lymphocytic leukemia (B-CLL) harbored a mutation (G12S and G12A, respectively) in the K-ras gene, and one B-CLL harbored a mutation (Q61R) in the N-ras gene. 9139869

1997

dbSNP: rs121913254
rs121913254
0.010 GeneticVariation BEFREE Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H). 22575864

2012

dbSNP: rs121913255
rs121913255
0.010 GeneticVariation BEFREE Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H). 22575864

2012

dbSNP: rs1239470707
rs1239470707
0.010 GeneticVariation BEFREE Mutations of the BRAF gene were identified in six (24%) diffuse large B-cell lymphomas (D594G in three germinal center diffuse large B-cell lymphomas, K601N in two germinal center diffuse large B-cell lymphomas, and V600E in one non-germinal center diffuse large B-cell lymphoma) and of the NRAS gene in two (8%) non-germinal center diffuse large B-cell lymphomas (Q61K and Q61H). 22575864

2012

dbSNP: rs111724149
rs111724149
0.700 GeneticVariation UNIPROT

dbSNP: rs35090414
rs35090414
0.700 GeneticVariation UNIPROT

dbSNP: rs1312391542
rs1312391542
0.010 GeneticVariation BEFREE A single-base substitution was found in exon 1 (227G>A) of the XBP1 gene in a patient with diffuse large B-cell lymphoma, resulting in a somatic missense mutation (R76K). 19380033

2009

dbSNP: rs3758391
rs3758391
0.010 GeneticVariation BEFREE SIRT1 rs3758391 polymorphism and risk of diffuse large B cell lymphoma in a Chinese population. 30377410

2018

dbSNP: rs2736098
rs2736098
0.010 GeneticVariation BEFREE Association of MNS16A VNTR and hTERT rs2736098: G>A polymorphisms with susceptibility to diffuse large B-cell lymphoma. 28967095

2018

dbSNP: rs1801195
rs1801195
WRN
0.010 GeneticVariation BEFREE A significant interaction with BMI was only observed for WRN (rs1801195; P = 0.004) for T-cell lymphoma and ERCC2 (rs13181; P = 0.002) for diffuse large B-cell lymphoma. 23619945

2013