|
rs749280481
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Mutational analysis of TSSC5 by direct DNA sequencing of exons revealed a base substitution of G1120A in a Wilms' tumor, matched normal kidney, and the patient's mother, changed Arg at codon 309 to Gln.
|
9751628 |
1998 |
|
rs121913409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three mutations, Ser45Phe (TCT --> TTT), Ser45Tyr (TCT --> TAT), and Delta45 (deletion of TCT), were found in 3 of 19 unilateral WTs.
|
12239584 |
2002 |
|
rs1423753702
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report on a novel WT1 nonsense mutation (c.1105C>T), introducing a premature stop codon in exon 8 (p.Q369X), in a young XY male patient who presented with bilateral cryptorchidism, nystagmus, mild proteinuria and WT, but no sign of severe nephropathy.
|
19048299 |
2009 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Impact of the MTHFR C677T polymorphism on risk of Wilms tumor: case-control study.
|
19346876 |
2009 |
|
rs2857461
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One SNP in EWSR1 (rs2857461) showed a low level of statistical association with the diagnosis of Ewing sarcoma compared to Wilms tumor.
|
21793187 |
2012 |
|
rs662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The presence of at least one variant PON1 rs662 R allele increased the risk of developing Wilms´ Tumor although without statistical power.
|
24972570 |
2014 |
|
rs121912657
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We show that (i) in the choroid plexus carcinoma, the germline mutation was detected in a homozygous state due to copy-neutral LOH/uniparental disomy, (ii) in the secondary AML, a complex karyotype led to loss of the wild-type TP53 allele, (iii) in the Wilms tumor, the somatic mutation c.814G>A led to compound heterozygosity.
|
25787918 |
2015 |
|
rs16754
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The genetic variant rs16754 of Wilms tumor gene 1 (WT1) has recently been described as an independent prognostic factor in AML patients.
|
25932444 |
2015 |
|
rs10972727
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that the G allele of rs11788747 in the RECK gene was significantly associated with WT in Chinese children (OR=0.7, 95% CI: 0.45-0.99; P=0.042); as with another SNP rs10972727, however, no statistically significant difference was detected.
|
26141647 |
2015 |
|
rs11788747
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The present data indicate that there is a significant association between mutant G of rs11788747 in RECK and WT risk.
|
26141647 |
2015 |
|
rs16754
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Wilms tumor gene single nucleotide polymorphism rs16754 predicts a favorable outcome in children with acute lymphoblastic leukemia.
|
26224397 |
2015 |
|
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Overall, our result suggested a lack of association between the <i>TP53</i> gene Arg72Pro polymorphism and Wilms' tumor.
|
28260929 |
2017 |
|
rs1131691014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, our result suggested a lack of association between the <i>TP53</i> gene Arg72Pro polymorphism and Wilms' tumor.
|
28260929 |
2017 |
|
rs878854066
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall, our result suggested a lack of association between the <i>TP53</i> gene Arg72Pro polymorphism and Wilms' tumor.
|
28260929 |
2017 |
|
rs314276
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, these results indicated that the LIN28B gene rs314276 C>A polymorphism alone and three combined polymorphisms may be able to modify WT susceptibility in Southern Chinese children.
|
28301057 |
2018 |
|
rs110419
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only rs110419 AG was found to be protective against Wilms' tumor (adjusted OR = 0.62, 95% CI = 0.41-0.94, <i>P</i> = 0.024) when compared to rs110419 AA.
|
28881592 |
2017 |
|
rs9404576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that HACE1 rs9404576 polymorphism may be associated with Wilms' tumor susceptibility in the Chinese population.
|
29243987 |
2017 |
|
rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations with Wilms tumor susceptibility were shown for hOGG1 rs1052133 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.96, P = .030), FEN1 rs174538 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.95, P = .027; recessive: adjusted OR = 0.54, 95% CI = 0.32-0.93 P = .027), and FEN1 rs4246215 (dominant: adjusted OR = 0.55, 95% CI = 0.38-0.80, P = .002) polymorphisms.
|
29937070 |
2018 |
|
rs174538
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations with Wilms tumor susceptibility were shown for hOGG1 rs1052133 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.96, P = .030), FEN1 rs174538 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.95, P = .027; recessive: adjusted OR = 0.54, 95% CI = 0.32-0.93 P = .027), and FEN1 rs4246215 (dominant: adjusted OR = 0.55, 95% CI = 0.38-0.80, P = .002) polymorphisms.
|
29937070 |
2018 |
|
rs4246215
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations with Wilms tumor susceptibility were shown for hOGG1 rs1052133 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.96, P = .030), FEN1 rs174538 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.95, P = .027; recessive: adjusted OR = 0.54, 95% CI = 0.32-0.93 P = .027), and FEN1 rs4246215 (dominant: adjusted OR = 0.55, 95% CI = 0.38-0.80, P = .002) polymorphisms.
|
29937070 |
2018 |
|
rs6505162
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, the <i>miR-423</i> rs6505162 C>A polymorphism may negatively modify WT susceptibility in Chinese children.
|
30026843 |
2018 |
|
rs3810366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The XPD rs3810366 polymorphism significantly enhanced Wilms tumor risk (dominant model: adjusted OR = 2.12, 95% CI = 1.26-3.57).
|
30161024 |
2018 |
|
rs1042522
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The effect of rs1042522 C>G polymorphism on Wilms tumor prevalence was analyzed using logistic regression models.
|
30610160 |
2019 |
|
rs12587
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification analysis revealed that rs12587 GT/TT was associated with Wilms tumor risk in children >18 months old (adjusted OR=1.39, 95% CI=1.02-1.89, <i>P</i>=0.037).
|
30860980 |
2019 |
|
rs1059111
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association between rs11994014 G>A or rs1059111 A>T polymorphisms and Wilms' tumor susceptibility did not reach statistical significance.
|
31057612 |
2019 |