|
rs11994014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association between rs11994014 G>A or rs1059111 A>T polymorphisms and Wilms' tumor susceptibility did not reach statistical significance.
|
31057612 |
2019 |
|
rs8173
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our findings indicated that the <i>AURKA</i> rs8173 G>C polymorphism was associated with decreased Wilms tumor risk in Chinese children.
|
31636670 |
2019 |
|
rs113488022
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, we demonstrate that BRA</span>F V600E mutations are not entirely restricted to typical MA, as they may be seen in MAs showing mitotic activity along with a subset of epithelial-predominant WTs in adults and children that have foci which overlap morphologically with MA.
|
31192863 |
2019 |
|
rs121913377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, we demonstrate that BRA</span>F V600E mutations are not entirely restricted to typical MA, as they may be seen in MAs showing mitotic activity along with a subset of epithelial-predominant WTs in adults and children that have foci which overlap morphologically with MA.
|
31192863 |
2019 |
|
rs121913409
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Three mutations, Ser45Phe (TCT --> TTT), Ser45Tyr (TCT --> TAT), and Delta45 (deletion of TCT), were found in 3 of 19 unilateral WTs.
|
12239584 |
2002 |
|
rs3810366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The XPD rs3810366 polymorphism significantly enhanced Wilms tumor risk (dominant model: adjusted OR = 2.12, 95% CI = 1.26-3.57).
|
30161024 |
2018 |
|
rs2857461
|
|
|
0.010 |
GeneticVariation |
BEFREE |
One SNP in EWSR1 (rs2857461) showed a low level of statistical association with the diagnosis of Ewing sarcoma compared to Wilms tumor.
|
21793187 |
2012 |
|
rs4246215
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations with Wilms tumor susceptibility were shown for hOGG1 rs1052133 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.96, P = .030), FEN1 rs174538 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.95, P = .027; recessive: adjusted OR = 0.54, 95% CI = 0.32-0.93 P = .027), and FEN1 rs4246215 (dominant: adjusted OR = 0.55, 95% CI = 0.38-0.80, P = .002) polymorphisms.
|
29937070 |
2018 |
|
rs9404576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicated that HACE1 rs9404576 polymorphism may be associated with Wilms' tumor susceptibility in the Chinese population.
|
29243987 |
2017 |
|
rs8756
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We carried out the first four-center case-control study with 355 patients and 1070 controls to assess the association of HMGA2 polymorphisms (rs6581658 A>G, rs8756 A>C, and rs968697 T>C) with Wilms tumor risk.
|
31746066 |
2019 |
|
rs6581658
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We carried out the first four-center case-control study with 355 patients and 1070 controls to assess the association of HMGA2 polymorphisms (rs6581658 A>G, rs8756 A>C, and rs968697 T>C) with Wilms tumor risk.
|
31746066 |
2019 |
|
rs968697
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We firstly demonstrated that rs6581658 A>G, rs8756 A>C, and rs968697 T>C could not impact Wilms tumor risk, respectively.
|
31746066 |
2019 |
|
rs12587
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Stratification analysis revealed that rs12587 GT/TT was associated with Wilms tumor risk in children >18 months old (adjusted OR=1.39, 95% CI=1.02-1.89, <i>P</i>=0.037).
|
30860980 |
2019 |
|
rs314276
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, these results indicated that the LIN28B gene rs314276 C>A polymorphism alone and three combined polymorphisms may be able to modify WT susceptibility in Southern Chinese children.
|
28301057 |
2018 |
|
rs11655237
|
|
|
0.020 |
GeneticVariation |
BEFREE |
These data could be useful for reinforcing our understanding of the potential contribution of LINC00673 rs11655237 C>T to Wilms tumor susceptibility.
|
31657076 |
2019 |
|
rs11655237
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In conclusion, we failed to find any association between the LINC00673 rs11655237 C>T polymorphism and WT risk.
|
31257678 |
2019 |
|
rs110419
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only rs110419 AG was found to be protective against Wilms' tumor (adjusted OR = 0.62, 95% CI = 0.41-0.94, <i>P</i> = 0.024) when compared to rs110419 AA.
|
28881592 |
2017 |
|
rs2168101
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These results suggest that <i>LMO1</i> gene rs2168101 G>T polymorphism may help prevent Wilms tumor, but this conclusion should be verified in other populations and additional studies.
|
31205537 |
2019 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Impact of the MTHFR C677T polymorphism on risk of Wilms tumor: case-control study.
|
19346876 |
2009 |
|
rs57961569
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interestingly, in the stratification analysis, the rs57961569 was found to be associated with decreased Wilms tumor susceptibility in the children older than 18 months (AOR = 0.65, 95% CI = 0.42-1.00, P = .050).
|
31343784 |
2019 |
|
rs1059111
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The association between rs11994014 G>A or rs1059111 A>T polymorphisms and Wilms' tumor susceptibility did not reach statistical significance.
|
31057612 |
2019 |
|
rs2979704
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggested that the <i>NEFL</i> rs2979704 T>C polymorphism may be associated with Wilms' tumor susceptibility in the Chinese population.
|
31057612 |
2019 |
|
rs6505162
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In summary, the <i>miR-423</i> rs6505162 C>A polymorphism may negatively modify WT susceptibility in Chinese children.
|
30026843 |
2018 |
|
rs1052133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations with Wilms tumor susceptibility were shown for hOGG1 rs1052133 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.96, P = .030), FEN1 rs174538 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.95, P = .027; recessive: adjusted OR = 0.54, 95% CI = 0.32-0.93 P = .027), and FEN1 rs4246215 (dominant: adjusted OR = 0.55, 95% CI = 0.38-0.80, P = .002) polymorphisms.
|
29937070 |
2018 |
|
rs28647582
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our study suggested that PHOX2B rs28647582 T>C was weakly associated with Wilms tumor susceptibility.
|
31652452 |
2019 |