Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913279
rs121913279
PIK3CA
0.020 GeneticVariation BEFREE Induction of PIK3CA(H1047R) expression in mouse mammary glands with constitutive expression of activated Her2/Neu resulted in accelerated mammary tumorigenesis with enhanced metastatic potential. 26640141

2016
dbSNP: rs121913279
rs121913279
PIK3CA
0.020 GeneticVariation BEFREE Conditional activation of Pik3ca(H1047R) in a knock-in mouse model promotes mammary tumorigenesis and emergence of mutations. 22370636

2013
dbSNP: rs749539903
rs749539903
ERBB2 ; MIR4728
0.010 GeneticVariation BEFREE Induction of PIK3CA(H1047R) expression in mouse mammary glands with constitutive expression of activated Her2/Neu resulted in accelerated mammary tumorigenesis with enhanced metastatic potential. 26640141

2016
dbSNP: rs759106015
rs759106015
EGFR
0.010 GeneticVariation BEFREE To examine the role of mutant p53 during ErbB2-mediated mammary tumorigenesis, a mutant p53 allele (R172H) was introduced into the (MMTV)-ErbB2/Neu mouse model system. 25573952

2015
dbSNP: rs763371007
rs763371007
ERBB2
0.010 GeneticVariation BEFREE To examine the role of mutant p53 during ErbB2-mediated mammary tumorigenesis, a mutant p53 allele (R172H) was introduced into the (MMTV)-ErbB2/Neu mouse model system. 25573952

2015
dbSNP: rs896171398
rs896171398
ERBB2
0.010 GeneticVariation BEFREE To examine the role of mutant p53 during ErbB2-mediated mammary tumorigenesis, a mutant p53 allele (R172H) was introduced into the (MMTV)-ErbB2/Neu mouse model system. 25573952

2015