Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs118101777
rs118101777
IDH2
0.010 GeneticVariation BEFREE IDH1 (R132H) mutation was observed in 5/75 primary GBs. 31479414

2020
dbSNP: rs121913500
rs121913500
IDH1
0.010 GeneticVariation BEFREE IDH1 (R132H) mutation was observed in 5/75 primary GBs. 31479414

2020
dbSNP: rs113488022
rs113488022
BRAF
0.010 GeneticVariation BEFREE Two of four MN1 intact cases by FISH showed genetic features of either anaplastic pleomorphic xanthoastrocytoma (BRAF p.V600E mutation, CDKN2A/B homozygous deletion and TERT promoter mutation) or IDH-wildtype glioblastoma (trisomy 7, monosomy 10, CDK4 amplification and TP53, NRAS and TERT promoter mutations) and these cases had an aggressive clinical course. 28960623

2018
dbSNP: rs121913377
rs121913377
BRAF
0.010 GeneticVariation BEFREE Two of four MN1 intact cases by FISH showed genetic features of either anaplastic pleomorphic xanthoastrocytoma (BRAF p.V600E mutation, CDKN2A/B homozygous deletion and TERT promoter mutation) or IDH-wildtype glioblastoma (trisomy 7, monosomy 10, CDK4 amplification and TP53, NRAS and TERT promoter mutations) and these cases had an aggressive clinical course. 28960623

2018