Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12932445
rs12932445
0.700 GeneticVariation GWASCAT Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354

2018

dbSNP: rs13143308
rs13143308
0.700 GeneticVariation GWASCAT Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354

2018

dbSNP: rs146390073
rs146390073
0.700 GeneticVariation GWASCAT Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354

2018

dbSNP: rs635634
rs635634
0.700 GeneticVariation GWASCAT Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354

2018

dbSNP: rs6891174
rs6891174
0.700 GeneticVariation GWASCAT Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354

2018

dbSNP: rs2200733
rs2200733
0.030 GeneticVariation BEFREE In the Icelandic samples and the two replication sets combined, rs2200733 associated significantly with cardioembolic stroke (CES) (odds ratio [OR], 1.54; p = 8.05 x 10(-9)). 18991354

2008

dbSNP: rs2200733
rs2200733
0.030 GeneticVariation BEFREE The rs2200733 variant on chromosome 4q25 is a risk factor for cardioembolic stroke related to atrial fibrillation in Polish patients. 21574119

2011

dbSNP: rs2200733
rs2200733
0.030 GeneticVariation BEFREE Subsequently subgroup analysis indicated that both rs2200733 and rs10033464 conferred increased risk for cardioembolic stroke (CE stroke) (for rs2200733, OR 1.38, 95 % CI 1.26-1.51; for rs10033464, OR 1.14, 95 % CI 1.02-1.26), while rs2200733 was marginal associated with non-CE stroke (OR 1.09, 95 % CI 1.02-1.16). our results demonstrated that two SNPs (rs2200733 and rs1003346) on chromosome 4q25 were limited to the stroke of cardioembolic etiology. 24065534

2013

dbSNP: rs152312
rs152312
0.020 GeneticVariation BEFREE Our findings demonstrated an association between cardioembolic stroke and phosphodiesterase 4D single nucleotide polymorphisms rs152312 and 45. 21989204

2011

dbSNP: rs152312
rs152312
0.020 GeneticVariation BEFREE The rs152312 SNP was associated with cardioembolic stroke among whites after multiple comparison corrections. 16373644

2006

dbSNP: rs1003346
rs1003346
0.010 GeneticVariation BEFREE Subsequently subgroup analysis indicated that both rs2200733 and rs10033464 conferred increased risk for cardioembolic stroke (CE stroke) (for rs2200733, OR 1.38, 95 % CI 1.26-1.51; for rs10033464, OR 1.14, 95 % CI 1.02-1.26), while rs2200733 was marginal associated with non-CE stroke (OR 1.09, 95 % CI 1.02-1.16). our results demonstrated that two SNPs (rs2200733 and rs1003346) on chromosome 4q25 were limited to the stroke of cardioembolic etiology. 24065534

2013

dbSNP: rs10033464
rs10033464
0.010 GeneticVariation BEFREE Subsequently subgroup analysis indicated that both rs2200733 and rs10033464 conferred increased risk for cardioembolic stroke (CE stroke) (for rs2200733, OR 1.38, 95 % CI 1.26-1.51; for rs10033464, OR 1.14, 95 % CI 1.02-1.26), while rs2200733 was marginal associated with non-CE stroke (OR 1.09, 95 % CI 1.02-1.16). our results demonstrated that two SNPs (rs2200733 and rs1003346) on chromosome 4q25 were limited to the stroke of cardioembolic etiology. 24065534

2013

dbSNP: rs1205
rs1205
CRP
0.010 GeneticVariation BEFREE Three polymorphisms, rs1205 (CRP gene), rs1800779, and rs2257073 (NOS3 gene), were associated with cardioembolic stroke (p value <0.05). 26355258

2015

dbSNP: rs1217691063
rs1217691063
0.010 GeneticVariation BEFREE MTHFR C677T was associated with magnetic resonance imaging-confirmed lacunar stroke, but not large artery or cardioembolic stroke. 26839351

2016

dbSNP: rs151091899
rs151091899
0.010 GeneticVariation BEFREE The analysis of the TRPV3 gene using polymorphisms in cohort 3 and 4 revealed two polymorphisms associated with cardioembolic stroke in both cohorts, the most significant polymorphism being rs151091899 (p-value: 3.1 × 10<sup>-05</sup>; odds ratio: 5.4) in cohort 3. 27604134

2016

dbSNP: rs1800779
rs1800779
0.010 GeneticVariation BEFREE Three polymorphisms, rs1205 (CRP gene), rs1800779, and rs2257073 (NOS3 gene), were associated with cardioembolic stroke (p value <0.05). 26355258

2015

dbSNP: rs1906591
rs1906591
0.010 GeneticVariation BEFREE Variant rs1906591 on chromosome 4q25 confers increased risk of cardioembolic stroke in Chinese patients. 24932589

2014

dbSNP: rs20417
rs20417
0.010 GeneticVariation BEFREE In the Boston cohort, rs20417 polymorphism was associated with increased WMHv among noncardioembolic (P = .037), but not among cardioembolic stroke patients. 25957909

2015

dbSNP: rs2257073
rs2257073
0.010 GeneticVariation BEFREE Three polymorphisms, rs1205 (CRP gene), rs1800779, and rs2257073 (NOS3 gene), were associated with cardioembolic stroke (p value <0.05). 26355258

2015

dbSNP: rs2273235
rs2273235
0.010 GeneticVariation BEFREE Similar results were found for m<sup>6</sup>A-SNP rs2273235 in the <i>NDST1</i> gene which was associated with cardioembolic stroke (<i>P</i> = 8.47 × 10<sup>-3</sup>). 31156544

2019

dbSNP: rs2910829
rs2910829
0.010 GeneticVariation BEFREE Although several univariate associations were identified, only 1 SNP (rs2910829) was found to be significantly associated with cardioembolic stroke among both whites and blacks. 16373644

2006

dbSNP: rs505922
rs505922
ABO
0.010 GeneticVariation BEFREE Independent replication in Meta-Stroke confirmed the rs505922 association with stroke, beta (standard error, SE) = 0.066 (0.02), p = 0.001, a finding specific to large-vessel and cardioembolic stroke (p = 0.001 and p = < 0.001, respectively) but not seen with small-vessel stroke (p = 0.811). 23381943

2013

dbSNP: rs5065
rs5065
0.010 GeneticVariation BEFREE However, in logistic analysis for Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification of ischemic stroke, nonsynonymous rs5065 (STOP152Arg) and rs5067 in 3'UTR of NPPA, which were in complete linkage disequilibrium, showed significant associations with cardioembolic stroke. 22400494

2012

dbSNP: rs5067
rs5067
0.010 GeneticVariation BEFREE However, in logistic analysis for Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification of ischemic stroke, nonsynonymous rs5065 (STOP152Arg) and rs5067 in 3'UTR of NPPA, which were in complete linkage disequilibrium, showed significant associations with cardioembolic stroke. 22400494

2012

dbSNP: rs761740955
rs761740955
FGB
0.010 GeneticVariation BEFREE The β-fibrinogen gene 455G/A polymorphism associated with cardioembolic stroke in atrial fibrillation with low CHA<sub>2</sub>DS<sub>2</sub>-VaSc score. 29235504

2017