|
rs151264360
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The 6-bp deletion [rs151264360, OR: 0.79 (0.20-3.19)] was not associated with the development of MTX-induced oral mucositis.
|
30222710 |
2018 |
|
rs1629816
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study was to investigate the relationship between single nucleotide polymorphisms (SNP; rs1629816) in the regulatory region (c.-2531C>T) of the ghrelin (GHRL) gene and the occurrence and severity of oral mucositis caused by radiotherapy (RT) in patients with head and neck cancer.
|
29566446 |
2018 |
|
rs34743033
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The 2R2R genotype (rs34743033) was not significantly associated with developing MTX-induced oral mucositis compared with the 2R3R/3R3R genotypes, which was confirmed in a meta-analysis [odds ratio (OR): 1.17 (0.62-2.19)].
|
30222710 |
2018 |
|
rs4149570
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results indicate an association between SNP of TNFRSF1A (rs4149570) gene and risk of more severe OM related to radiation therapy for HNC patients.
|
28401452 |
2018 |
|
rs4855883
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphism of regulatory region of APEH gene (c.-521G>C, rs4855883) as a relevant predictive factor for radiotherapy induced oral mucositis and overall survival in head neck cancer patients.
|
30038710 |
2018 |
|
rs10505168
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Oral mucositis was defined as grade more than or equal to 3 according to the National Cancer Institute criteria. rs2114358 in miR-1206 was associated with oral mucositis [odds ratio (OR): 3.6; 95% confidence interval (CI): 1.1-11.5], whereas we did not confirm the association of CNOT4 rs3812265 (OR: 0.69; 95% CI: 0.27-1.80) and miR-2053 rs10505168 (OR: 2.50; 95% CI: 0.76-8.24).
|
28628559 |
2017 |
|
rs11081899
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggested that rs11081899-A may be a genetic susceptibility factor for radiation-induced OM in patients with NPC, although its value in clinical application needs to be further verified in a large cohort.
|
28968968 |
2017 |
|
rs12676482
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In some subgroups, cyclin D1 gene CCND1 rs9344 and inhibitor of κB kinase gene IKBKB rs12676482 were related with the grade 3-4 acute radiation-induced myelosuppression, and CCND1 rs9344 was also associated with grade 3-4 acute radiation-induced oral mucositis.
|
28445979 |
2017 |
|
rs2114358
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Oral mucositis was defined as grade more than or equal to 3 according to the National Cancer Institute criteria. rs2114358 in miR-1206 was associated with oral mucositis [odds ratio (OR): 3.6; 95% confidence interval (CI): 1.1-11.5], whereas we did not confirm the association of CNOT4 rs3812265 (OR: 0.69; 95% CI: 0.27-1.80) and miR-2053 rs10505168 (OR: 2.50; 95% CI: 0.76-8.24).
|
28628559 |
2017 |
|
rs3812265
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Oral mucositis was defined as grade more than or equal to 3 according to the National Cancer Institute criteria. rs2114358 in miR-1206 was associated with oral mucositis [odds ratio (OR): 3.6; 95% confidence interval (CI): 1.1-11.5], whereas we did not confirm the association of CNOT4 rs3812265 (OR: 0.69; 95% CI: 0.27-1.80) and miR-2053 rs10505168 (OR: 2.50; 95% CI: 0.76-8.24).
|
28628559 |
2017 |
|
rs9344
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In some subgroups, cyclin D1 gene CCND1 rs9344 and inhibitor of κB kinase gene IKBKB rs12676482 were related with the grade 3-4 acute radiation-induced myelosuppression, and CCND1 rs9344 was also associated with grade 3-4 acute radiation-induced oral mucositis.
|
28445979 |
2017 |
|
rs375557
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, GSK3β rs375557 and adenomatous polyposis coli gene (APC) rs454886 polymorphisms were correlated with acute grade 3-4 radiation-induced dermatitis and oral mucositis, respectively.
|
27769064 |
2016 |
|
rs454886
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Moreover, GSK3β rs375557 and adenomatous polyposis coli gene (APC) rs454886 polymorphisms were correlated with acute grade 3-4 radiation-induced dermatitis and oral mucositis, respectively.
|
27769064 |
2016 |
|
rs25487
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our investigation shows, for the first time, that patients with the XRCC1 399Arg/Gln genotype were more likely to experience severe acute dermatitis and oral mucositis.
|
23375119 |
2013 |
|
rs1045642
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Is the MDR1 C3435T polymorphism responsible for oral mucositis in children with acute lymphoblastic leukemia?
|
23244145 |
2012 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results suggested that MTHFR C677T polymorphism was associated with significantly increased risk of MTX-induced toxicity, specifically liver toxicity (TT/CT vs. CC: odds ratio (OR) = 1.70, 95 % confidence interval (CI) = 1.05-2.75), myelosuppression (TT vs. CT/CC: OR = 2.82, 95 %CI = 1.25-6.34), oral mucositis (TT/CT vs. CC: OR = 3.68, 95 %CI = 1.73-7.85), gastrointestinal toxicity (TT/CT vs. CC: OR = 2.36, 95 %CI = 1.36-4.11), and skin toxicity (T vs. C: OR = 2.26, 95 %CI = 1.07-4.74).
|
22528943 |
2012 |