Gene: TP53 ×
Source: INFERRED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs28934574
rs28934574
TP53
A 0.700 CausalMutation CLINVAR Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms. 1565144

1992
dbSNP: rs28934575
rs28934575
TP53
T 0.700 CausalMutation CLINVAR Screening for germ line TP53 mutations in breast cancer patients. 1591732

1992
dbSNP: rs28934575
rs28934575
TP53
T 0.700 CausalMutation CLINVAR Prevalence and spectrum of germline mutations of the p53 gene among patients with sarcoma. 1565143

1992
dbSNP: rs28934576
rs28934576
TP53
T 0.700 CausalMutation CLINVAR Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms. 1565144

1992
dbSNP: rs28934576
rs28934576
TP53
T 0.700 GeneticVariation CLINVAR Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms. 1565144

1992
dbSNP: rs397514495
rs397514495
TP53
T 0.700 GeneticVariation CLINVAR Screening for germ line TP53 mutations in breast cancer patients. 1591732

1992
dbSNP: rs397514495
rs397514495
TP53
T 0.700 GeneticVariation CLINVAR Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein. 1631137

1992
dbSNP: rs397516436
rs397516436
TP53
A 0.700 CausalMutation CLINVAR Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome. 7887414

1995
dbSNP: rs28934574
rs28934574
TP53
A 0.700 CausalMutation CLINVAR Molecular analysis of the TP53 gene in Barrett's adenocarcinoma. 8829627

1996
dbSNP: rs11540652
rs11540652
TP53
T 0.700 GeneticVariation CLINVAR Germ-line mutations of TP53 in Li-Fraumeni families: an extended study of 39 families. 9242456

1997
dbSNP: rs28934575
rs28934575
TP53
T 0.700 CausalMutation CLINVAR Simple identification of dominant p53 mutants by a yeast functional assay. 9364015

1997
dbSNP: rs28934578
rs28934578
TP53
T 0.700 CausalMutation CLINVAR A detailed study of loss of heterozygosity on chromosome 17 in tumours from Li-Fraumeni patients carrying a mutation to the TP53 gene. 9047394

1997
dbSNP: rs587783062
rs587783062
TP53
A 0.700 GeneticVariation CLINVAR Li-Fraumeni syndrome--a molecular and clinical review. 9218725

1997
dbSNP: rs879253942
rs879253942
TP53
G 0.700 GeneticVariation CLINVAR Three germline mutations in the TP53 gene. 9067756

1997
dbSNP: rs28934575
rs28934575
TP53
T 0.700 CausalMutation CLINVAR Comprehensive mutational scanning of the p53 coding region by two-dimensional gene scanning. 9667734

1998
dbSNP: rs397516436
rs397516436
TP53
A 0.700 CausalMutation CLINVAR Comprehensive mutational scanning of the p53 coding region by two-dimensional gene scanning. 9667734

1998
dbSNP: rs587783062
rs587783062
TP53
A 0.700 GeneticVariation CLINVAR Cancer phenotype correlates with constitutional TP53 genotype in families with the Li-Fraumeni syndrome. 9764816

1998
dbSNP: rs121912664
rs121912664
TP53
T 0.700 CausalMutation CLINVAR P53 germline mutations in childhood cancers and cancer risk for carrier individuals. 10864200

2000
dbSNP: rs121913343
rs121913343
TP53
A 0.700 CausalMutation CLINVAR A patient with 17 primary tumours and a germ line mutation in TP53: tumour induction by adjuvant therapy? 11315715

2000
dbSNP: rs121913343
rs121913343
TP53
A 0.700 CausalMutation CLINVAR P53 germline mutations in childhood cancers and cancer risk for carrier individuals. 10864200

2000
dbSNP: rs28934575
rs28934575
TP53
T 0.700 CausalMutation CLINVAR Absence of germline p16(INK4a) alterations in p53 wild type Li-Fraumeni syndrome families. 10922393

2000
dbSNP: rs11540652
rs11540652
TP53
T 0.700 CausalMutation CLINVAR Germline TP53 alterations in Finnish breast cancer families are rare and occur at conserved mutation-prone sites. 11139324

2001
dbSNP: rs121913343
rs121913343
TP53
A 0.700 CausalMutation CLINVAR Tissue-specific expression of SV40 in tumors associated with the Li-Fraumeni syndrome. 11494139

2001
dbSNP: rs28934574
rs28934574
TP53
A 0.700 CausalMutation CLINVAR Detection of 11 germline inactivating TP53 mutations and absence of TP63 and HCHK2 mutations in 17 French families with Li-Fraumeni or Li-Fraumeni-like syndrome. 11370630

2001
dbSNP: rs28934575
rs28934575
TP53
T 0.700 CausalMutation CLINVAR Detection of 11 germline inactivating TP53 mutations and absence of TP63 and HCHK2 mutations in 17 French families with Li-Fraumeni or Li-Fraumeni-like syndrome. 11370630

2001