| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
C | 0.700 | CausalMutation | CLINVAR | JAK mutations in high-risk childhood acute lymphoblastic leukemia. | 19470474 | 2009 |
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|
A | 0.700 | GeneticVariation | CLINVAR | Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. | 19838194 | 2009 |
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|
A | 0.700 | GeneticVariation | CLINVAR | JAK mutations in high-risk childhood acute lymphoblastic leukemia. | 19470474 | 2009 |
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|
A | 0.700 | GeneticVariation | CLINVAR | Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers. | 19139102 | 2009 |
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|
G | 0.700 | CausalMutation | CLINVAR | Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome. | 18805579 | 2008 |
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|
C | 0.700 | CausalMutation | CLINVAR | Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome. | 18805579 | 2008 |
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|
C | 0.700 | CausalMutation | CLINVAR | Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome. | 18805579 | 2008 |
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|
T | 0.700 | CausalMutation | CLINVAR | Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome. | 18805579 | 2008 |
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|
C | 0.700 | GeneticVariation | CLINVAR | Kinase domain point mutations in Philadelphia chromosome-positive acute lymphoblastic leukemia emerge after therapy with BCR-ABL kinase inhibitors. | 18615627 | 2008 |
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|
T | 0.700 | GeneticVariation | CLINVAR | Ph(+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation. | 11861307 | 2002 |
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|
C | 0.700 | GeneticVariation | CLINVAR | BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study. | 11853795 | 2002 |