Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2036914
rs2036914
F11
0.830 GeneticVariation BEFREE Our findings suggest that the risk of VTE by FHMI is not explained by rs8176719 (ABO), rs6025 (F5), rs1799963 (F2), rs2066865 (FGG), and rs2036914 (F11). 31124268

2019

dbSNP: rs2036914
rs2036914
F11
0.830 GeneticVariation BEFREE The meta-analysis revealed that the F11 rs2289252, F11 rs2036914, FGG rs2066865, and CYP4V2 rs13146272 polymorphisms were closely related to the development of VTE in the white race under the best genetic models after multiple testing adjustments. 28353616

2017

dbSNP: rs2036914
rs2036914
F11
0.830 GeneticVariation BEFREE In F11, the CC genotype for rs2036914 and the CT and TT genotypes for rs2289252 were associated with a significantly higher VTE risk. 23150947

2013

dbSNP: rs3756008
rs3756008
F11
0.810 GeneticVariation BEFREE A nucleotide variant (rs3756008) in the promoter region of the FXI gene was recently reported for association with venous thromboembolism. 24420855

2014

dbSNP: rs2289252
rs2289252
0.740 GeneticVariation BEFREE The meta-analysis revealed that the F11 rs2289252, F11 rs2036914, FGG rs2066865, and CYP4V2 rs13146272 polymorphisms were closely related to the development of VTE in the white race under the best genetic models after multiple testing adjustments. 28353616

2017

dbSNP: rs2289252
rs2289252
0.740 GeneticVariation BEFREE In conclusion, F5 rs6025 and F11 rs2289252 contributed to the risk of recurrent VTE and the combination is of potential clinical relevance for risk prediction. 26423325

2016

dbSNP: rs2289252
rs2289252
0.740 GeneticVariation BEFREE Seven SNPs (F5 rs6025, F2 rs1799963, ABO rs514659, FGG rs2066865, F11 rs2289252, PROC rs1799810 and KNG1 rs710446) with four SNP-SNP interactions contributed to the genetic risk score for VTE, with an AUC of 0.66 (95% CI, 0.64-0.68). 25472531

2015

dbSNP: rs2289252
rs2289252
0.740 GeneticVariation BEFREE In F11, the CC genotype for rs2036914 and the CT and TT genotypes for rs2289252 were associated with a significantly higher VTE risk. 23150947

2013

dbSNP: rs925451
rs925451
F11
0.710 GeneticVariation BEFREE After Bonferroni adjustment, four single nucleotide polymorphisms (SNPs) were significantly associated with VTE: Factor XI rs925451 polymorphism, factor XI rs2289252 polymorphism, factor II rs1799963 (G20210A) polymorphism and factor V Leiden rs6025. 20352152

2010