Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4752028
rs4752028
0.010 GeneticVariation BEFREE This is the first study to find a relationship between these two loci on 10q25 (rs4752028 and rs7078160) and NSOFC in a population with high levels of consanguinity. 30633559

2019

dbSNP: rs7078160
rs7078160
0.010 GeneticVariation BEFREE This is the first study to find a relationship between these two loci on 10q25 (rs4752028 and rs7078160) and NSOFC in a population with high levels of consanguinity. 30633559

2019

dbSNP: rs2910164
rs2910164
0.010 GeneticVariation BEFREE Taken together, these results demonstrated that miR-146a/rs2910164 is associated with susceptibility to NSOC, providing novel insights into the genetic etiology and underlying biology of NSOC. 29484780

2018

dbSNP: rs2124459
rs2124459
CBS
0.010 GeneticVariation BEFREE Within the CBS haplotype block (rs2124459, rs6586282, rs4920037, rs234705, rs234709), the rs2124459 was the most significantly associated with a reduced risk of OFC (p=1.77×10<sup>-4</sup>; Bonferroni p=2.00×10<sup>-2</sup>; OR 0.53 (0.38 to 0.74), minor allele). 27535090

2016

dbSNP: rs234705
rs234705
CBS
0.010 GeneticVariation BEFREE Within the CBS haplotype block (rs2124459, rs6586282, rs4920037, rs234705, rs234709), the rs2124459 was the most significantly associated with a reduced risk of OFC (p=1.77×10<sup>-4</sup>; Bonferroni p=2.00×10<sup>-2</sup>; OR 0.53 (0.38 to 0.74), minor allele). 27535090

2016

dbSNP: rs234709
rs234709
CBS
0.010 GeneticVariation BEFREE Within the CBS haplotype block (rs2124459, rs6586282, rs4920037, rs234705, rs234709), the rs2124459 was the most significantly associated with a reduced risk of OFC (p=1.77×10<sup>-4</sup>; Bonferroni p=2.00×10<sup>-2</sup>; OR 0.53 (0.38 to 0.74), minor allele). 27535090

2016

dbSNP: rs1076562
rs1076562
0.010 GeneticVariation BEFREE These SNPs also showed moderate association with increased prolactin in olanzapine-treated and OFC-treated women in the meta-analysis, as did rs4938016, rs2734848, rs2734841, rs1124493, and rs1076562. 21095016

2011

dbSNP: rs2855530
rs2855530
0.010 GeneticVariation BEFREE The sex-dependent association between rs2855530 and NSCLP could indirectly be related to the differential gene expression observed between sexes in animal models. 22182590

2011

dbSNP: rs4938016
rs4938016
0.010 GeneticVariation BEFREE These SNPs also showed moderate association with increased prolactin in olanzapine-treated and OFC-treated women in the meta-analysis, as did rs4938016, rs2734848, rs2734841, rs1124493, and rs1076562. 21095016

2011

dbSNP: rs1801131
rs1801131
0.010 GeneticVariation BEFREE The aim of this study was to investigate the effects of maternal riboflavin intake and two MTHFR polymorphisms (677C>T; Ala222Val and 1298A>C; Glu429Ala substitutions) on the biomarkers of the homocysteine pathway, and investigate the risk of having offspring with an orofacial cleft (OFC). 19935819

2010

dbSNP: rs397507444
rs397507444
0.010 GeneticVariation BEFREE In a case-control study design, dietary riboflavin intake and the MTHFR 677C>T and 1298A>C polymorphisms were evaluated in 123 OFC and 108 control mothers by using food frequency questionnaires and blood samples. 19935819

2010