Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1267969615
rs1267969615
ACE
0.060 GeneticVariation BEFREE Co-existing angiotensinogen M235T AGT polymorphism and two other common polymorphisms of the RAS genes are related to adverse events in patients with CAD. 21769789

2011

dbSNP: rs1267969615
rs1267969615
ACE
0.060 GeneticVariation BEFREE In conclusion, our results suggest that a significantly higher risk of CAD was associated with the Ins/Del, the M235T, and T174M polymorphisms; other environmental variables such as body mass index; and biochemical variables such as cholesterol. 20854100

2010

dbSNP: rs1267969615
rs1267969615
ACE
0.060 GeneticVariation BEFREE No association between AGT M235T, AGT T174M, ACE I/D and AT(1) receptor A1166C polymorphisms and CAD was observed. 20223792

2010

dbSNP: rs1267969615
rs1267969615
ACE
0.060 GeneticVariation BEFREE Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. Prospective Cardiac Gene. 11345362

2001

dbSNP: rs1267969615
rs1267969615
ACE
0.060 GeneticVariation BEFREE In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic regression analysis was used to study the relationships among, on the one hand, the insertion/deletion gene polymorphism of the angiotensin-converting enzyme gene (ACE-ID), the M235T gene polymorphism of the angiotensinogen gene (AGT-M235T), and the A1166C gene polymorphism of the angiotensin type 1 receptor gene (AT1-A1166C), and, on the other hand, UAE, retinopathy, hypertension, and coronary heart disease. 10862638

2000

dbSNP: rs1267969615
rs1267969615
ACE
0.060 GeneticVariation BEFREE These associations did not disappear when the analyses were corrected for multiple comparisons for other gene polymorphisms (ACE I/D gene variation, angiotensinogen T174M and M235T gene polymorphisms, AT1 receptor gene variation, phox C242T gene polymorphism, paraoxonase PON54 and PON191 gene variations) (2p = 0.01 in MLR for the presence of CAD; 2p = 0.039 in multiple regression for the extent of CAD). 10488959

1999

dbSNP: rs1799752
rs1799752
ACE
0.030 GeneticVariation BEFREE This study aimed to verify the possible influence of apolipoprotein B (ApoB: rs1042031 and rs693) and angiotensin-converting enzyme (ACE-ID: rs1799752) genotypes on the lipid profile and functional aerobic capacity, respectively, after an aerobic interval training (AIT) program in patients with CAD and/or cardiovascular risk factors. 29846435

2018

dbSNP: rs1799752
rs1799752
ACE
0.030 GeneticVariation BEFREE The univariate analysis indicated that the five variants; rs1800595 (FVR2; factor 5), rs1801133 (MTHFR; 5,10-methylenetetrahydrofolate reductase), rs5918 (HPA-1; human platelet antigen 1), rs1799752 (ACE; angiotensin-converting enzyme), and rs7412 and rs429358 (ApoE; apolipoprotein E) were significantly associated with CAD susceptibility under different genetic models. 28086795

2017

dbSNP: rs1799752
rs1799752
ACE
0.030 GeneticVariation BEFREE Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease. 27162064

2016

dbSNP: rs1205538057
rs1205538057
ACE
0.010 GeneticVariation BEFREE A slight impact of AT2R 1675G/A polymorphism on CAD was found only in female diabetic patients. 22345093

2012

dbSNP: rs4291
rs4291
ACE
0.010 GeneticVariation BEFREE Four polymorphisms, located in the ACE (rs4291), angiotensinogen (rs5049) and (pro)renin receptor (rs2968915; rs5981008) genes were significantly associated with hypertension in two vascular disease populations of CAD (EUROPA) and cerebrovascular disease (PROGRESS; n = 3571). 21157371

2011

dbSNP: rs767425642
rs767425642
ACE
0.010 GeneticVariation BEFREE We evaluated the risk of CAD associated with PON1 Q192R and L55M polymorphisms in 298 CAD patients and 298 healthy individuals. 19280995

2008

dbSNP: rs142677199
rs142677199
ACE
0.010 GeneticVariation BEFREE Our observations allow the assumption that the p22 phox A640G gene polymorphism is independently associated with the presence and extent of coronary artery disease. 10488959

1999

dbSNP: rs761401927
rs761401927
ACE
0.010 GeneticVariation BEFREE Our observations allow the assumption that the p22 phox A640G gene polymorphism is independently associated with the presence and extent of coronary artery disease. 10488959

1999